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Genetically diverse mouse models of SARS-CoV-2 infection reproduce clinical variation in type I interferon and cytokine responses in COVID-19.

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Title: Genetically diverse mouse models of SARS-CoV-2 infection reproduce clinical variation in type I interferon and cytokine responses in COVID-19.
Authors: Robertson SJ; Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT, USA.; Laboratory of Neurological Infections and Immunity, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT, USA., Bedard O; The Jackson Laboratory, Bar Harbor, ME, USA., McNally KL; Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT, USA., Shaia C; Rocky Mountain Veterinary Branch, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT, USA., Clancy CS; Rocky Mountain Veterinary Branch, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT, USA., Lewis M; Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT, USA., Broeckel RM; Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT, USA., Chiramel AI; Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT, USA., Shannon JG; Laboratory of Neurological Infections and Immunity, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT, USA., Sturdevant GL; Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT, USA.; Laboratory of Neurological Infections and Immunity, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT, USA., Rosenke R; Rocky Mountain Veterinary Branch, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT, USA., Anzick SL; Research Technologies Branch, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA., Forte E; The Jackson Laboratory, Bar Harbor, ME, USA.; Springer Nature, New York, NY, USA., Preuss C; The Jackson Laboratory, Bar Harbor, ME, USA., Baker CN; The Jackson Laboratory, Bar Harbor, ME, USA., Harder JM; The Jackson Laboratory, Bar Harbor, ME, USA., Brunton C; The Jackson Laboratory, Bar Harbor, ME, USA., Munger S; The Jackson Laboratory, Bar Harbor, ME, USA., Bruno DP; Research Technologies Branch, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA., Lack JB; Research Technologies Branch, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA., Leung JM; Research Technologies Branch, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA., Shamsaddini A; Research Technologies Branch, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA., Gardina P; Research Technologies Branch, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA., Sturdevant DE; Research Technologies Branch, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA., Sun J; Research Technologies Branch, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA., Martens C; Research Technologies Branch, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA., Holland SM; Division of Intramural Research, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA., Rosenthal NA; The Jackson Laboratory, Bar Harbor, ME, USA. Nadia.Rosenthal@jax.com.; National Heart and Lung Institute, Imperial College London, London, UK. Nadia.Rosenthal@jax.com., Best SM; Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT, USA. sbest@niaid.nih.gov.; Laboratory of Neurological Infections and Immunity, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT, USA. sbest@niaid.nih.gov.
Source: Nature communications [Nat Commun] 2023 Jul 25; Vol. 14 (1), pp. 4481. Date of Electronic Publication: 2023 Jul 25.
Publication Type: Journal Article; Research Support, N.I.H., Intramural
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Genetically diverse mouse models of SARS-CoV-2 infection reproduce clinical variation in type I interferon and cytokine responses in COVID-19.
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  Data: <searchLink fieldCode="AU" term="%22Robertson+SJ%22">Robertson SJ</searchLink>; Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT, USA.; Laboratory of Neurological Infections and Immunity, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT, USA.<br /><searchLink fieldCode="AU" term="%22Bedard+O%22">Bedard O</searchLink>; The Jackson Laboratory, Bar Harbor, ME, USA.<br /><searchLink fieldCode="AU" term="%22McNally+KL%22">McNally KL</searchLink>; Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT, USA.<br /><searchLink fieldCode="AU" term="%22Shaia+C%22">Shaia C</searchLink>; Rocky Mountain Veterinary Branch, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT, USA.<br /><searchLink fieldCode="AU" term="%22Clancy+CS%22">Clancy CS</searchLink>; Rocky Mountain Veterinary Branch, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT, USA.<br /><searchLink fieldCode="AU" term="%22Lewis+M%22">Lewis M</searchLink>; Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT, USA.<br /><searchLink fieldCode="AU" term="%22Broeckel+RM%22">Broeckel RM</searchLink>; Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT, USA.<br /><searchLink fieldCode="AU" term="%22Chiramel+AI%22">Chiramel AI</searchLink>; Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT, USA.<br /><searchLink fieldCode="AU" term="%22Shannon+JG%22">Shannon JG</searchLink>; Laboratory of Neurological Infections and Immunity, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT, USA.<br /><searchLink fieldCode="AU" term="%22Sturdevant+GL%22">Sturdevant GL</searchLink>; Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT, USA.; Laboratory of Neurological Infections and Immunity, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT, USA.<br /><searchLink fieldCode="AU" term="%22Rosenke+R%22">Rosenke R</searchLink>; Rocky Mountain Veterinary Branch, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT, USA.<br /><searchLink fieldCode="AU" term="%22Anzick+SL%22">Anzick SL</searchLink>; Research Technologies Branch, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Forte+E%22">Forte E</searchLink>; The Jackson Laboratory, Bar Harbor, ME, USA.; Springer Nature, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Preuss+C%22">Preuss C</searchLink>; The Jackson Laboratory, Bar Harbor, ME, USA.<br /><searchLink fieldCode="AU" term="%22Baker+CN%22">Baker CN</searchLink>; The Jackson Laboratory, Bar Harbor, ME, USA.<br /><searchLink fieldCode="AU" term="%22Harder+JM%22">Harder JM</searchLink>; The Jackson Laboratory, Bar Harbor, ME, USA.<br /><searchLink fieldCode="AU" term="%22Brunton+C%22">Brunton C</searchLink>; The Jackson Laboratory, Bar Harbor, ME, USA.<br /><searchLink fieldCode="AU" term="%22Munger+S%22">Munger S</searchLink>; The Jackson Laboratory, Bar Harbor, ME, USA.<br /><searchLink fieldCode="AU" term="%22Bruno+DP%22">Bruno DP</searchLink>; Research Technologies Branch, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Lack+JB%22">Lack JB</searchLink>; Research Technologies Branch, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Leung+JM%22">Leung JM</searchLink>; Research Technologies Branch, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Shamsaddini+A%22">Shamsaddini A</searchLink>; Research Technologies Branch, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Gardina+P%22">Gardina P</searchLink>; Research Technologies Branch, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Sturdevant+DE%22">Sturdevant DE</searchLink>; Research Technologies Branch, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Sun+J%22">Sun J</searchLink>; Research Technologies Branch, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Martens+C%22">Martens C</searchLink>; Research Technologies Branch, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Holland+SM%22">Holland SM</searchLink>; Division of Intramural Research, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Rosenthal+NA%22">Rosenthal NA</searchLink>; The Jackson Laboratory, Bar Harbor, ME, USA. Nadia.Rosenthal@jax.com.; National Heart and Lung Institute, Imperial College London, London, UK. Nadia.Rosenthal@jax.com.<br /><searchLink fieldCode="AU" term="%22Best+SM%22">Best SM</searchLink>; Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT, USA. sbest@niaid.nih.gov.; Laboratory of Neurological Infections and Immunity, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT, USA. sbest@niaid.nih.gov.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2023 Jul 25; Vol. 14 (1), pp. 4481. <i>Date of Electronic Publication: </i>2023 Jul 25.
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