Increased genital mucosal cytokines in Canadian women associate with higher antigen-presenting cells, inflammatory metabolites, epithelial barrier disruption, and the depletion of L. crispatus.

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Title: Increased genital mucosal cytokines in Canadian women associate with higher antigen-presenting cells, inflammatory metabolites, epithelial barrier disruption, and the depletion of L. crispatus.
Authors: Farr Zuend C; Center for Global Health and Diseases, Department of Pathology, Case Western Reserve University, Cleveland, USA. christina.farr@case.edu., Lamont A; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Canada., Noel-Romas L; Center for Global Health and Diseases, Department of Pathology, Case Western Reserve University, Cleveland, USA.; Department of Obstetrics, Gynecology & Reproductive Sciences, University of Manitoba, Winnipeg, Canada., Knodel S; Center for Global Health and Diseases, Department of Pathology, Case Western Reserve University, Cleveland, USA.; Department of Obstetrics, Gynecology & Reproductive Sciences, University of Manitoba, Winnipeg, Canada., Birse K; Center for Global Health and Diseases, Department of Pathology, Case Western Reserve University, Cleveland, USA.; Department of Obstetrics, Gynecology & Reproductive Sciences, University of Manitoba, Winnipeg, Canada., Kratzer K; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Canada., McQueen P; JC Wilt Infectious Disease Research Centre, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada., Perner M; JC Wilt Infectious Disease Research Centre, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada., Ayele H; Center for Global Health and Diseases, Department of Pathology, Case Western Reserve University, Cleveland, USA.; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Canada., Mutch S; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Canada., Berard AR; Center for Global Health and Diseases, Department of Pathology, Case Western Reserve University, Cleveland, USA.; Department of Obstetrics, Gynecology & Reproductive Sciences, University of Manitoba, Winnipeg, Canada., Schellenberg JJ; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Canada., Senturk F; Center for Global Health and Diseases, Department of Pathology, Case Western Reserve University, Cleveland, USA., McCorrister S; JC Wilt Infectious Disease Research Centre, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada., Westmacott G; JC Wilt Infectious Disease Research Centre, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada., Mulhall F; Health Sciences Centre, Winnipeg, Canada., Sandberg B; Health Sciences Centre, Winnipeg, Canada., Yu A; Department of Obstetrics, Gynecology & Reproductive Sciences, University of Manitoba, Winnipeg, Canada., Burnett M; Department of Obstetrics, Gynecology & Reproductive Sciences, University of Manitoba, Winnipeg, Canada., Poliquin V; Department of Obstetrics, Gynecology & Reproductive Sciences, University of Manitoba, Winnipeg, Canada., Burgener AD; Center for Global Health and Diseases, Department of Pathology, Case Western Reserve University, Cleveland, USA. adam.burgener@case.edu.; Department of Obstetrics, Gynecology & Reproductive Sciences, University of Manitoba, Winnipeg, Canada. adam.burgener@case.edu.; Unit of Infectious Diseases, Department of Medicine Solna, Center for Molecular Medicine, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden. adam.burgener@case.edu.
Source: Microbiome [Microbiome] 2023 Jul 25; Vol. 11 (1), pp. 159. Date of Electronic Publication: 2023 Jul 25.
Publication Type: Video-Audio Media; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101615147 Publication Model: Electronic Cited Medium: Internet ISSN: 2049-2618 (Electronic) Linking ISSN: 20492618 NLM ISO Abbreviation: Microbiome Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2049-2618
DOI:10.1186/s40168-023-01594-y