Increased genital mucosal cytokines in Canadian women associate with higher antigen-presenting cells, inflammatory metabolites, epithelial barrier disruption, and the depletion of L. crispatus.

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Title: Increased genital mucosal cytokines in Canadian women associate with higher antigen-presenting cells, inflammatory metabolites, epithelial barrier disruption, and the depletion of L. crispatus.
Authors: Farr Zuend C; Center for Global Health and Diseases, Department of Pathology, Case Western Reserve University, Cleveland, USA. christina.farr@case.edu., Lamont A; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Canada., Noel-Romas L; Center for Global Health and Diseases, Department of Pathology, Case Western Reserve University, Cleveland, USA.; Department of Obstetrics, Gynecology & Reproductive Sciences, University of Manitoba, Winnipeg, Canada., Knodel S; Center for Global Health and Diseases, Department of Pathology, Case Western Reserve University, Cleveland, USA.; Department of Obstetrics, Gynecology & Reproductive Sciences, University of Manitoba, Winnipeg, Canada., Birse K; Center for Global Health and Diseases, Department of Pathology, Case Western Reserve University, Cleveland, USA.; Department of Obstetrics, Gynecology & Reproductive Sciences, University of Manitoba, Winnipeg, Canada., Kratzer K; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Canada., McQueen P; JC Wilt Infectious Disease Research Centre, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada., Perner M; JC Wilt Infectious Disease Research Centre, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada., Ayele H; Center for Global Health and Diseases, Department of Pathology, Case Western Reserve University, Cleveland, USA.; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Canada., Mutch S; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Canada., Berard AR; Center for Global Health and Diseases, Department of Pathology, Case Western Reserve University, Cleveland, USA.; Department of Obstetrics, Gynecology & Reproductive Sciences, University of Manitoba, Winnipeg, Canada., Schellenberg JJ; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Canada., Senturk F; Center for Global Health and Diseases, Department of Pathology, Case Western Reserve University, Cleveland, USA., McCorrister S; JC Wilt Infectious Disease Research Centre, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada., Westmacott G; JC Wilt Infectious Disease Research Centre, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada., Mulhall F; Health Sciences Centre, Winnipeg, Canada., Sandberg B; Health Sciences Centre, Winnipeg, Canada., Yu A; Department of Obstetrics, Gynecology & Reproductive Sciences, University of Manitoba, Winnipeg, Canada., Burnett M; Department of Obstetrics, Gynecology & Reproductive Sciences, University of Manitoba, Winnipeg, Canada., Poliquin V; Department of Obstetrics, Gynecology & Reproductive Sciences, University of Manitoba, Winnipeg, Canada., Burgener AD; Center for Global Health and Diseases, Department of Pathology, Case Western Reserve University, Cleveland, USA. adam.burgener@case.edu.; Department of Obstetrics, Gynecology & Reproductive Sciences, University of Manitoba, Winnipeg, Canada. adam.burgener@case.edu.; Unit of Infectious Diseases, Department of Medicine Solna, Center for Molecular Medicine, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden. adam.burgener@case.edu.
Source: Microbiome [Microbiome] 2023 Jul 25; Vol. 11 (1), pp. 159. Date of Electronic Publication: 2023 Jul 25.
Publication Type: Video-Audio Media; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101615147 Publication Model: Electronic Cited Medium: Internet ISSN: 2049-2618 (Electronic) Linking ISSN: 20492618 NLM ISO Abbreviation: Microbiome Subsets: MEDLINE
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  Data: Increased genital mucosal cytokines in Canadian women associate with higher antigen-presenting cells, inflammatory metabolites, epithelial barrier disruption, and the depletion of L. crispatus.
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  Data: <searchLink fieldCode="AU" term="%22Farr+Zuend+C%22">Farr Zuend C</searchLink>; Center for Global Health and Diseases, Department of Pathology, Case Western Reserve University, Cleveland, USA. christina.farr@case.edu.<br /><searchLink fieldCode="AU" term="%22Lamont+A%22">Lamont A</searchLink>; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Canada.<br /><searchLink fieldCode="AU" term="%22Noel-Romas+L%22">Noel-Romas L</searchLink>; Center for Global Health and Diseases, Department of Pathology, Case Western Reserve University, Cleveland, USA.; Department of Obstetrics, Gynecology & Reproductive Sciences, University of Manitoba, Winnipeg, Canada.<br /><searchLink fieldCode="AU" term="%22Knodel+S%22">Knodel S</searchLink>; Center for Global Health and Diseases, Department of Pathology, Case Western Reserve University, Cleveland, USA.; Department of Obstetrics, Gynecology & Reproductive Sciences, University of Manitoba, Winnipeg, Canada.<br /><searchLink fieldCode="AU" term="%22Birse+K%22">Birse K</searchLink>; Center for Global Health and Diseases, Department of Pathology, Case Western Reserve University, Cleveland, USA.; Department of Obstetrics, Gynecology & Reproductive Sciences, University of Manitoba, Winnipeg, Canada.<br /><searchLink fieldCode="AU" term="%22Kratzer+K%22">Kratzer K</searchLink>; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Canada.<br /><searchLink fieldCode="AU" term="%22McQueen+P%22">McQueen P</searchLink>; JC Wilt Infectious Disease Research Centre, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.<br /><searchLink fieldCode="AU" term="%22Perner+M%22">Perner M</searchLink>; JC Wilt Infectious Disease Research Centre, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.<br /><searchLink fieldCode="AU" term="%22Ayele+H%22">Ayele H</searchLink>; Center for Global Health and Diseases, Department of Pathology, Case Western Reserve University, Cleveland, USA.; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Canada.<br /><searchLink fieldCode="AU" term="%22Mutch+S%22">Mutch S</searchLink>; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Canada.<br /><searchLink fieldCode="AU" term="%22Berard+AR%22">Berard AR</searchLink>; Center for Global Health and Diseases, Department of Pathology, Case Western Reserve University, Cleveland, USA.; Department of Obstetrics, Gynecology & Reproductive Sciences, University of Manitoba, Winnipeg, Canada.<br /><searchLink fieldCode="AU" term="%22Schellenberg+JJ%22">Schellenberg JJ</searchLink>; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Canada.<br /><searchLink fieldCode="AU" term="%22Senturk+F%22">Senturk F</searchLink>; Center for Global Health and Diseases, Department of Pathology, Case Western Reserve University, Cleveland, USA.<br /><searchLink fieldCode="AU" term="%22McCorrister+S%22">McCorrister S</searchLink>; JC Wilt Infectious Disease Research Centre, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.<br /><searchLink fieldCode="AU" term="%22Westmacott+G%22">Westmacott G</searchLink>; JC Wilt Infectious Disease Research Centre, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.<br /><searchLink fieldCode="AU" term="%22Mulhall+F%22">Mulhall F</searchLink>; Health Sciences Centre, Winnipeg, Canada.<br /><searchLink fieldCode="AU" term="%22Sandberg+B%22">Sandberg B</searchLink>; Health Sciences Centre, Winnipeg, Canada.<br /><searchLink fieldCode="AU" term="%22Yu+A%22">Yu A</searchLink>; Department of Obstetrics, Gynecology & Reproductive Sciences, University of Manitoba, Winnipeg, Canada.<br /><searchLink fieldCode="AU" term="%22Burnett+M%22">Burnett M</searchLink>; Department of Obstetrics, Gynecology & Reproductive Sciences, University of Manitoba, Winnipeg, Canada.<br /><searchLink fieldCode="AU" term="%22Poliquin+V%22">Poliquin V</searchLink>; Department of Obstetrics, Gynecology & Reproductive Sciences, University of Manitoba, Winnipeg, Canada.<br /><searchLink fieldCode="AU" term="%22Burgener+AD%22">Burgener AD</searchLink>; Center for Global Health and Diseases, Department of Pathology, Case Western Reserve University, Cleveland, USA. adam.burgener@case.edu.; Department of Obstetrics, Gynecology & Reproductive Sciences, University of Manitoba, Winnipeg, Canada. adam.burgener@case.edu.; Unit of Infectious Diseases, Department of Medicine Solna, Center for Molecular Medicine, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden. adam.burgener@case.edu.
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  Data: <searchLink fieldCode="JN" term="%22101615147%22">Microbiome</searchLink> [Microbiome] 2023 Jul 25; Vol. 11 (1), pp. 159. <i>Date of Electronic Publication: </i>2023 Jul 25.
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