NPC1-dependent alterations in KV2.1-CaV1.2 nanodomains drive neuronal death in models of Niemann-Pick Type C disease.

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Title: NPC1-dependent alterations in KV2.1-CaV1.2 nanodomains drive neuronal death in models of Niemann-Pick Type C disease.
Authors: Casas M; Department of Physiology and Membrane Biology, School of Medicine, University of California, Davis, CA, USA., Murray KD; Department of Physiology and Membrane Biology, School of Medicine, University of California, Davis, CA, USA.; Department of Psychiatry & Behavioral Sciences, School of Medicine, University of California, Davis, CA, USA., Hino K; Department of Cell Biology and Human Anatomy, School of Medicine, University of California, Davis, CA, USA., Vierra NC; Department of Physiology and Membrane Biology, School of Medicine, University of California, Davis, CA, USA., Simó S; Department of Cell Biology and Human Anatomy, School of Medicine, University of California, Davis, CA, USA., Trimmer JS; Department of Physiology and Membrane Biology, School of Medicine, University of California, Davis, CA, USA., Dixon RE; Department of Physiology and Membrane Biology, School of Medicine, University of California, Davis, CA, USA., Dickson EJ; Department of Physiology and Membrane Biology, School of Medicine, University of California, Davis, CA, USA. ejdickson@ucdavis.edu.
Source: Nature communications [Nat Commun] 2023 Jul 28; Vol. 14 (1), pp. 4553. Date of Electronic Publication: 2023 Jul 28.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2041-1723
DOI:10.1038/s41467-023-39937-w