Computational modeling and synthesis of pyridine variants of benzoyl-phenoxy-acetamide with high glioblastoma cytotoxicity and brain tumor penetration.
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| Title: | Computational modeling and synthesis of pyridine variants of benzoyl-phenoxy-acetamide with high glioblastoma cytotoxicity and brain tumor penetration. |
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| Authors: | Ingraham CH 4th; Department of Chemistry, University of New Orleans, New Orleans, LA, 70148, USA.; Neurological Cancer Research, Department of Medicine, Stanley S. Scott Cancer Center, LSU Health Sciences Center, New Orleans, LA, 70112, USA.; Neurological Cancer Research, Department of Interdisciplinary Oncology, LSU Health Sciences Center, New Orleans, LA, 70112, USA.; WayPath Pharma, New Orleans BioInnovation Center (NOBIC), 1441 Canal Str., New Orleans, LA, 70112, USA., Stalinska J; Neurological Cancer Research, Department of Medicine, Stanley S. Scott Cancer Center, LSU Health Sciences Center, New Orleans, LA, 70112, USA.; Neurological Cancer Research, Department of Interdisciplinary Oncology, LSU Health Sciences Center, New Orleans, LA, 70112, USA.; Department of Cell Biology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Cracow, Poland., Carson SC; Department of Chemistry, University of New Orleans, New Orleans, LA, 70148, USA., Colley SB; Neurological Cancer Research, Department of Medicine, Stanley S. Scott Cancer Center, LSU Health Sciences Center, New Orleans, LA, 70112, USA.; Neurological Cancer Research, Department of Interdisciplinary Oncology, LSU Health Sciences Center, New Orleans, LA, 70112, USA.; Grants and Development Office, Stanley S. Scott Cancer Center, LSU Health Sciences Center, New Orleans, LA, 70112, USA., Rak M; Neurological Cancer Research, Department of Medicine, Stanley S. Scott Cancer Center, LSU Health Sciences Center, New Orleans, LA, 70112, USA.; Neurological Cancer Research, Department of Interdisciplinary Oncology, LSU Health Sciences Center, New Orleans, LA, 70112, USA.; Department of Cell Biology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Cracow, Poland., Lassak A; Neurological Cancer Research, Department of Medicine, Stanley S. Scott Cancer Center, LSU Health Sciences Center, New Orleans, LA, 70112, USA.; Neurological Cancer Research, Department of Interdisciplinary Oncology, LSU Health Sciences Center, New Orleans, LA, 70112, USA., Peruzzi F; Neurological Cancer Research, Department of Medicine, Stanley S. Scott Cancer Center, LSU Health Sciences Center, New Orleans, LA, 70112, USA.; Neurological Cancer Research, Department of Interdisciplinary Oncology, LSU Health Sciences Center, New Orleans, LA, 70112, USA., Reiss K; Neurological Cancer Research, Department of Medicine, Stanley S. Scott Cancer Center, LSU Health Sciences Center, New Orleans, LA, 70112, USA. kreiss@lsuhsc.edu.; Neurological Cancer Research, Department of Interdisciplinary Oncology, LSU Health Sciences Center, New Orleans, LA, 70112, USA. kreiss@lsuhsc.edu.; WayPath Pharma, New Orleans BioInnovation Center (NOBIC), 1441 Canal Str., New Orleans, LA, 70112, USA. kreiss@lsuhsc.edu., Jursic BS; Department of Chemistry, University of New Orleans, New Orleans, LA, 70148, USA. bjursic1@uno.edu.; Stepharm LLC., PO Box 24220, New Orleans, LA, 70184, USA. bjursic1@uno.edu. |
| Source: | Scientific reports [Sci Rep] 2023 Jul 28; Vol. 13 (1), pp. 12236. Date of Electronic Publication: 2023 Jul 28. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 37507404 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Computational modeling and synthesis of pyridine variants of benzoyl-phenoxy-acetamide with high glioblastoma cytotoxicity and brain tumor penetration. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Ingraham+CH+4th%22">Ingraham CH 4th</searchLink>; Department of Chemistry, University of New Orleans, New Orleans, LA, 70148, USA.; Neurological Cancer Research, Department of Medicine, Stanley S. Scott Cancer Center, LSU Health Sciences Center, New Orleans, LA, 70112, USA.; Neurological Cancer Research, Department of Interdisciplinary Oncology, LSU Health Sciences Center, New Orleans, LA, 70112, USA.; WayPath Pharma, New Orleans BioInnovation Center (NOBIC), 1441 Canal Str., New Orleans, LA, 70112, USA.<br /><searchLink fieldCode="AU" term="%22Stalinska+J%22">Stalinska J</searchLink>; Neurological Cancer Research, Department of Medicine, Stanley S. Scott Cancer Center, LSU Health Sciences Center, New Orleans, LA, 70112, USA.; Neurological Cancer Research, Department of Interdisciplinary Oncology, LSU Health Sciences Center, New Orleans, LA, 70112, USA.; Department of Cell Biology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Cracow, Poland.<br /><searchLink fieldCode="AU" term="%22Carson+SC%22">Carson SC</searchLink>; Department of Chemistry, University of New Orleans, New Orleans, LA, 70148, USA.<br /><searchLink fieldCode="AU" term="%22Colley+SB%22">Colley SB</searchLink>; Neurological Cancer Research, Department of Medicine, Stanley S. Scott Cancer Center, LSU Health Sciences Center, New Orleans, LA, 70112, USA.; Neurological Cancer Research, Department of Interdisciplinary Oncology, LSU Health Sciences Center, New Orleans, LA, 70112, USA.; Grants and Development Office, Stanley S. Scott Cancer Center, LSU Health Sciences Center, New Orleans, LA, 70112, USA.<br /><searchLink fieldCode="AU" term="%22Rak+M%22">Rak M</searchLink>; Neurological Cancer Research, Department of Medicine, Stanley S. Scott Cancer Center, LSU Health Sciences Center, New Orleans, LA, 70112, USA.; Neurological Cancer Research, Department of Interdisciplinary Oncology, LSU Health Sciences Center, New Orleans, LA, 70112, USA.; Department of Cell Biology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Cracow, Poland.<br /><searchLink fieldCode="AU" term="%22Lassak+A%22">Lassak A</searchLink>; Neurological Cancer Research, Department of Medicine, Stanley S. Scott Cancer Center, LSU Health Sciences Center, New Orleans, LA, 70112, USA.; Neurological Cancer Research, Department of Interdisciplinary Oncology, LSU Health Sciences Center, New Orleans, LA, 70112, USA.<br /><searchLink fieldCode="AU" term="%22Peruzzi+F%22">Peruzzi F</searchLink>; Neurological Cancer Research, Department of Medicine, Stanley S. Scott Cancer Center, LSU Health Sciences Center, New Orleans, LA, 70112, USA.; Neurological Cancer Research, Department of Interdisciplinary Oncology, LSU Health Sciences Center, New Orleans, LA, 70112, USA.<br /><searchLink fieldCode="AU" term="%22Reiss+K%22">Reiss K</searchLink>; Neurological Cancer Research, Department of Medicine, Stanley S. Scott Cancer Center, LSU Health Sciences Center, New Orleans, LA, 70112, USA. kreiss@lsuhsc.edu.; Neurological Cancer Research, Department of Interdisciplinary Oncology, LSU Health Sciences Center, New Orleans, LA, 70112, USA. kreiss@lsuhsc.edu.; WayPath Pharma, New Orleans BioInnovation Center (NOBIC), 1441 Canal Str., New Orleans, LA, 70112, USA. kreiss@lsuhsc.edu.<br /><searchLink fieldCode="AU" term="%22Jursic+BS%22">Jursic BS</searchLink>; Department of Chemistry, University of New Orleans, New Orleans, LA, 70148, USA. bjursic1@uno.edu.; Stepharm LLC., PO Box 24220, New Orleans, LA, 70184, USA. bjursic1@uno.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2023 Jul 28; Vol. 13 (1), pp. 12236. <i>Date of Electronic Publication: </i>2023 Jul 28. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101563288 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2045-2322 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220452322%22">20452322 </searchLink><i>NLM ISO Abbreviation: </i>Sci Rep <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=37507404 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41598-023-39236-w Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 12236 Titles: – TitleFull: Computational modeling and synthesis of pyridine variants of benzoyl-phenoxy-acetamide with high glioblastoma cytotoxicity and brain tumor penetration. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Ingraham CH 4th – PersonEntity: Name: NameFull: Stalinska J – PersonEntity: Name: NameFull: Carson SC – PersonEntity: Name: NameFull: Colley SB – PersonEntity: Name: NameFull: Rak M – PersonEntity: Name: NameFull: Lassak A – PersonEntity: Name: NameFull: Peruzzi F – PersonEntity: Name: NameFull: Reiss K – PersonEntity: Name: NameFull: Jursic BS IsPartOfRelationships: – BibEntity: Dates: – D: 28 M: 07 Text: 2023 Jul 28 Type: published Y: 2023 Identifiers: – Type: issn-electronic Value: 2045-2322 Numbering: – Type: volume Value: 13 – Type: issue Value: 1 Titles: – TitleFull: Scientific reports Type: main |
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