Structures of SARS-CoV-2 N7-methyltransferase with DOT1L and PRMT7 inhibitors provide a platform for new antivirals.
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| Title: | Structures of SARS-CoV-2 N7-methyltransferase with DOT1L and PRMT7 inhibitors provide a platform for new antivirals. |
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| Authors: | Kottur J; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America., White KM; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America., Rodriguez ML; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America., Rechkoblit O; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America., Quintana-Feliciano R; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America., Nayar A; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America., García-Sastre A; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.; Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.; The Tisch Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America., Aggarwal AK; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America. |
| Source: | PLoS pathogens [PLoS Pathog] 2023 Jul 31; Vol. 19 (7), pp. e1011546. Date of Electronic Publication: 2023 Jul 31 (Print Publication: 2023). |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1553-7374 |
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| DOI: | 10.1371/journal.ppat.1011546 |
