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Structures of SARS-CoV-2 N7-methyltransferase with DOT1L and PRMT7 inhibitors provide a platform for new antivirals.

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Title: Structures of SARS-CoV-2 N7-methyltransferase with DOT1L and PRMT7 inhibitors provide a platform for new antivirals.
Authors: Kottur J; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America., White KM; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America., Rodriguez ML; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America., Rechkoblit O; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America., Quintana-Feliciano R; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America., Nayar A; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America., García-Sastre A; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.; Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.; The Tisch Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America., Aggarwal AK; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
Source: PLoS pathogens [PLoS Pathog] 2023 Jul 31; Vol. 19 (7), pp. e1011546. Date of Electronic Publication: 2023 Jul 31 (Print Publication: 2023).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Structures of SARS-CoV-2 N7-methyltransferase with DOT1L and PRMT7 inhibitors provide a platform for new antivirals.
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  Data: <searchLink fieldCode="AU" term="%22Kottur+J%22">Kottur J</searchLink>; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.<br /><searchLink fieldCode="AU" term="%22White+KM%22">White KM</searchLink>; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.<br /><searchLink fieldCode="AU" term="%22Rodriguez+ML%22">Rodriguez ML</searchLink>; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.<br /><searchLink fieldCode="AU" term="%22Rechkoblit+O%22">Rechkoblit O</searchLink>; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.<br /><searchLink fieldCode="AU" term="%22Quintana-Feliciano+R%22">Quintana-Feliciano R</searchLink>; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.<br /><searchLink fieldCode="AU" term="%22Nayar+A%22">Nayar A</searchLink>; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.<br /><searchLink fieldCode="AU" term="%22García-Sastre+A%22">García-Sastre A</searchLink>; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.; Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.; The Tisch Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.<br /><searchLink fieldCode="AU" term="%22Aggarwal+AK%22">Aggarwal AK</searchLink>; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
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  Data: <searchLink fieldCode="JN" term="%22101238921%22">PLoS pathogens</searchLink> [PLoS Pathog] 2023 Jul 31; Vol. 19 (7), pp. e1011546. <i>Date of Electronic Publication: </i>2023 Jul 31 (<i>Print Publication: </i>2023).
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