Alkylation of nucleobases by 2-chloro-N,N-diethylethanamine hydrochloride (CDEAH) sensitizes PARP1-deficient tumors.

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Title:	Alkylation of nucleobases by 2-chloro-N,N-diethylethanamine hydrochloride (CDEAH) sensitizes PARP1-deficient tumors.
Authors:	Wie M; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea.; Department of Biological Sciences, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea., Khim KW; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea.; Department of Biological Sciences, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea., Groehler Iv AS; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea., Heo S; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea.; Department of Biomedical Engineering, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea., Woo J; Department of Chemistry, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea., Son K; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea., Lee EA; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea., Ra JS; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea., Hong SY; Department of Chemistry, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea., Schärer OD; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea.; Department of Biological Sciences, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea., Choi JH; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea.; Department of Biological Sciences, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea., Myung K; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea.; Department of Biomedical Engineering, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea.
Source:	NAR cancer [NAR Cancer] 2023 Aug 07; Vol. 5 (3), pp. zcad042. Date of Electronic Publication: 2023 Aug 07 (Print Publication: 2023).
Publication Type:	Journal Article
Journal Info:	Publisher: Oxford University Press Country of Publication: England NLM ID: 101769553 Publication Model: eCollection Cited Medium: Internet ISSN: 2632-8674 (Electronic) Linking ISSN: 26328674 NLM ISO Abbreviation: NAR Cancer Subsets: PubMed not MEDLINE
Database:	MEDLINE Ultimate

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ISSN:	2632-8674
DOI:	10.1093/narcan/zcad042