Safety and pharmacodynamic efficacy of eculizumab in aneurysmal subarachnoid hemorrhage (CLASH): A phase 2a randomized clinical trial.
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| Title: | Safety and pharmacodynamic efficacy of eculizumab in aneurysmal subarachnoid hemorrhage (CLASH): A phase 2a randomized clinical trial. |
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| Authors: | Koopman I; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Tack RW; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Wunderink HF; Department of Medical Microbiology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Bruns AH; Department of Internal Medicine and Infectious Diseases, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., van der Schaaf IC; Department of Radiology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Cianci D; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Gelderman KA; Sanquin Diagnostic Services, Amsterdam, The Netherlands., van de Ridder IM; Department of Intensive Care Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Hol EM; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Rinkel GJ; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Vergouwen MD; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands. |
| Source: | European stroke journal [Eur Stroke J] 2023 Dec; Vol. 8 (4), pp. 1097-1106. Date of Electronic Publication: 2023 Aug 22. |
| Publication Type: | Randomized Controlled Trial; Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: SAGE Publications Ltd Country of Publication: England NLM ID: 101688446 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2396-9881 (Electronic) Linking ISSN: 23969873 NLM ISO Abbreviation: Eur Stroke J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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