hGFAP-mediated GLI2 overexpression leads to early death and severe cerebellar malformations with rare tumor formation.

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Title: hGFAP-mediated GLI2 overexpression leads to early death and severe cerebellar malformations with rare tumor formation.
Authors: Niesen J; Mildred Scheel Cancer Career Centre HaTriCS4, University Medical Centre Hamburg-Eppendorf, 20251 Hamburg, Germany.; Research Institute Children's Cancer Centre, 20251 Hamburg, Germany.; Department of Pediatric Hematology and Oncology, University Medical Centre Hamburg-Eppendorf, 20251 Hamburg, Germany., Hermans-Borgmeyer I; Scientific Service Group for Transgenic Animals, University Medical Centre Hamburg-Eppendorf, 20251 Hamburg, Germany., Krüger C; Research Institute Children's Cancer Centre, 20251 Hamburg, Germany.; Department of Pediatric Hematology and Oncology, University Medical Centre Hamburg-Eppendorf, 20251 Hamburg, Germany., Schoof M; Research Institute Children's Cancer Centre, 20251 Hamburg, Germany.; Department of Pediatric Hematology and Oncology, University Medical Centre Hamburg-Eppendorf, 20251 Hamburg, Germany., Modemann F; Mildred Scheel Cancer Career Centre HaTriCS4, University Medical Centre Hamburg-Eppendorf, 20251 Hamburg, Germany.; Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, II. Department of Internal Medicine, University Medical Centre Hamburg-Eppendorf, 20251 Hamburg, Germany., Schüller U; Research Institute Children's Cancer Centre, 20251 Hamburg, Germany.; Department of Pediatric Hematology and Oncology, University Medical Centre Hamburg-Eppendorf, 20251 Hamburg, Germany.; Institute of Neuropathology, University Medical Centre Hamburg-Eppendorf, 20251 Hamburg, Germany.
Source: IScience [iScience] 2023 Jul 28; Vol. 26 (9), pp. 107501. Date of Electronic Publication: 2023 Jul 28 (Print Publication: 2023).
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2589-0042
DOI:10.1016/j.isci.2023.107501