An IgM-like inhalable ACE2 fusion protein broadly neutralizes SARS-CoV-2 variants.
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| Title: | An IgM-like inhalable ACE2 fusion protein broadly neutralizes SARS-CoV-2 variants. |
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| Authors: | Liu J; National Institute of Biological Sciences, Beijing, China.; Huahui Health Ltd, Beijing, China., Mao F; Huahui Health Ltd, Beijing, China., Chen J; Huahui Health Ltd, Beijing, China., Lu S; National Kunming High-level Biosafety Primate Research Center, Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Yunnan, China., Qi Y; Huahui Health Ltd, Beijing, China., Sun Y; National Institute of Biological Sciences, Beijing, China., Fang L; National Institute of Biological Sciences, Beijing, China., Yeung ML; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China.; State Key Laboratory of Emerging Infectious Diseases, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China.; Department of Clinical Microbiology and Infection Control, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong Province, China.; Carol Yu Centre for Infection, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China.; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Hong Kong Special Administrative Region, China., Liu C; Huahui Health Ltd, Beijing, China., Yu G; Huahui Health Ltd, Beijing, China., Li G; Huahui Health Ltd, Beijing, China., Liu X; National Institute of Biological Sciences, Beijing, China., Yao Y; Huahui Health Ltd, Beijing, China., Huang P; Huahui Health Ltd, Beijing, China., Hao D; Huahui Health Ltd, Beijing, China., Liu Z; Huahui Health Ltd, Beijing, China., Ding Y; Huahui Health Ltd, Beijing, China., Liu H; Huahui Health Ltd, Beijing, China., Yang F; Huahui Health Ltd, Beijing, China., Chen P; Huahui Health Ltd, Beijing, China., Sa R; Huahui Health Ltd, Beijing, China., Sheng Y; National Institute of Biological Sciences, Beijing, China., Tian X; National Institute of Biological Sciences, Beijing, China., Peng R; Huahui Health Ltd, Beijing, China., Li X; Huahui Health Ltd, Beijing, China., Luo J; Huahui Health Ltd, Beijing, China., Cheng Y; Huahui Health Ltd, Beijing, China., Zheng Y; Huahui Health Ltd, Beijing, China., Lin Y; Huahui Health Ltd, Beijing, China., Song R; Beijing Ditan Hospital, Capital Medical University, Beijing, China., Jin R; Beijing Ditan Hospital, Capital Medical University, Beijing, China., Huang B; National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention (China CDC), Beijing, China., Choe H; Department of Immunology and Microbiology, Scripps Research, Jupiter, FL, USA., Farzan M; Department of Immunology and Microbiology, Scripps Research, Jupiter, FL, USA., Yuen KY; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China.; State Key Laboratory of Emerging Infectious Diseases, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China.; Department of Clinical Microbiology and Infection Control, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong Province, China.; Carol Yu Centre for Infection, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China.; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Hong Kong Special Administrative Region, China., Tan W; National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention (China CDC), Beijing, China., Peng X; National Kunming High-level Biosafety Primate Research Center, Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Yunnan, China. pengxiaozhong@pumc.edu.cn.; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China. pengxiaozhong@pumc.edu.cn., Sui J; National Institute of Biological Sciences, Beijing, China. suijianhua@nibs.ac.cn.; Tsinghua Institute of Multidisciplinary Biomedical Research, Tsinghua University, Beijing, China. suijianhua@nibs.ac.cn., Li W; National Institute of Biological Sciences, Beijing, China. liwenhui@nibs.ac.cn.; Tsinghua Institute of Multidisciplinary Biomedical Research, Tsinghua University, Beijing, China. liwenhui@nibs.ac.cn. |
| Source: | Nature communications [Nat Commun] 2023 Aug 25; Vol. 14 (1), pp. 5191. Date of Electronic Publication: 2023 Aug 25. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-023-40933-3 |
