A blood-based marker of mitochondrial DNA damage in Parkinson's disease.
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| Title: | A blood-based marker of mitochondrial DNA damage in Parkinson's disease. |
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| Authors: | Qi R; Departments of Neurology and Pathology, Duke University School of Medicine, Durham, NC 27710, USA.; Duke Center for Neurodegeneration and Neurotherapeutics, Duke University, Durham, NC 27710, USA., Sammler E; Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, UK.; Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, DD1 5EH UK., Gonzalez-Hunt CP; Departments of Neurology and Pathology, Duke University School of Medicine, Durham, NC 27710, USA.; Duke Center for Neurodegeneration and Neurotherapeutics, Duke University, Durham, NC 27710, USA., Barraza I; Departments of Neurology and Pathology, Duke University School of Medicine, Durham, NC 27710, USA.; Duke Center for Neurodegeneration and Neurotherapeutics, Duke University, Durham, NC 27710, USA., Pena N; Departments of Neurology and Pathology, Duke University School of Medicine, Durham, NC 27710, USA.; Duke Center for Neurodegeneration and Neurotherapeutics, Duke University, Durham, NC 27710, USA., Rouanet JP; Departments of Neurology and Pathology, Duke University School of Medicine, Durham, NC 27710, USA., Naaldijk Y; Department of Anesthesiology and Department of Physiology, Pharmacology and Neuroscience, Rutgers New Jersey Medical School, Newark, NJ 07103, USA., Goodson S; Departments of Neurology and Pathology, Duke University School of Medicine, Durham, NC 27710, USA.; Duke Center for Neurodegeneration and Neurotherapeutics, Duke University, Durham, NC 27710, USA., Fuzzati M; IRCCS Mondino Foundation, National Institute of Neurology, Pavia 27100, Italy., Blandini F; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan 20122, Italy.; Department of Brain and Behavioral Sciences, University of Pavia, 27100 Pavia, Italy., Erickson KI; Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15213, USA.; AdventHealth Research Institute, Neuroscience, Orlando, FL 32804, USA., Weinstein AM; Department of Psychiatry, School of Medicine, University of Pittsburgh, PA 15213, USA., Lutz MW; Departments of Neurology and Pathology, Duke University School of Medicine, Durham, NC 27710, USA., Kwok JB; School of Medical Sciences, Faculty of Medicine and Health and the Brain and Mind Centre, University of Sydney, Camperdown, New South Wales 2050, Australia., Halliday GM; School of Medical Sciences, Faculty of Medicine and Health and the Brain and Mind Centre, University of Sydney, Camperdown, New South Wales 2050, Australia., Dzamko N; School of Medical Sciences, Faculty of Medicine and Health and the Brain and Mind Centre, University of Sydney, Camperdown, New South Wales 2050, Australia., Padmanabhan S; Michael J. Fox Foundation for Parkinson's Research, Grand Central Station, P.O. Box 4777, New York, NY 10120, USA., Alcalay RN; Columbia University Irving Medical Center, New York, NY 10032, USA.; Movement Disorders Unit, Neurological Institute, Tel Aviv Sourasky Medical Centre, Sackler School of Medicine, Sagol School of Neurosciences, Tel Aviv University, Tel Aviv, Israel., Waters C; Columbia University Irving Medical Center, New York, NY 10032, USA., Hogarth P; Departments of Molecular and Medical Genetics and Neurology, Oregon Health and Science University, Portland, OR 97239, USA., Simuni T; Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA., Smith D; Indiana University School of Medicine, Indianapolis, IN 46202, USA., Marras C; Edmond J. Safra Program in Parkinson's Disease, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Canada., Tonelli F; Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, DD1 5EH UK., Alessi DR; Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, DD1 5EH UK., West AB; Duke Center for Neurodegeneration and Neurotherapeutics, Duke University, Durham, NC 27710, USA.; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27710, USA., Shiva S; Department of Pharmacology and Chemical Biology and Medicine, Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA 15260, USA., Hilfiker S; Department of Anesthesiology and Department of Physiology, Pharmacology and Neuroscience, Rutgers New Jersey Medical School, Newark, NJ 07103, USA., Sanders LH; Departments of Neurology and Pathology, Duke University School of Medicine, Durham, NC 27710, USA.; Duke Center for Neurodegeneration and Neurotherapeutics, Duke University, Durham, NC 27710, USA. |
| Source: | Science translational medicine [Sci Transl Med] 2023 Aug 30; Vol. 15 (711), pp. eabo1557. Date of Electronic Publication: 2023 Aug 30. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1946-6242 |
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| DOI: | 10.1126/scitranslmed.abo1557 |
