The anti-CD40L monoclonal antibody AT-1501 promotes islet and kidney allograft survival and function in nonhuman primates.
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| Title: | The anti-CD40L monoclonal antibody AT-1501 promotes islet and kidney allograft survival and function in nonhuman primates. |
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| Authors: | Anwar IJ; Duke Transplant Center, Department of Surgery, Duke University School of Medicine; Durham, NC 27710, USA., Berman DM; Diabetes Research Institute, University of Miami, Miami, FL 33136, USA.; Department of Surgery, University of Miami, Miami, FL 33136, USA., DeLaura I; Duke Transplant Center, Department of Surgery, Duke University School of Medicine; Durham, NC 27710, USA., Gao Q; Duke Transplant Center, Department of Surgery, Duke University School of Medicine; Durham, NC 27710, USA., Willman MA; Diabetes Research Institute, University of Miami, Miami, FL 33136, USA., Miller A; Duke Transplant Center, Department of Surgery, Duke University School of Medicine; Durham, NC 27710, USA., Gill A; ALS Therapy Development Institute, Cambridge, MA 02472, USA., Gill C; ALS Therapy Development Institute, Cambridge, MA 02472, USA., Perrin S; Eledon Pharmaceuticals, Irving, CA 92612, USA., Ricordi C; Diabetes Research Institute, University of Miami, Miami, FL 33136, USA.; Department of Surgery, University of Miami, Miami, FL 33136, USA.; Department of Microbiology and Immunology, University of Miami, Miami, FL 33136, USA.; Department of Biomedical Engineering, University of Miami, Miami, FL 33136, USA.; Department of Medicine, University of Miami, Miami, FL 33136, USA., Ruiz P; Department of Surgery, University of Miami, Miami, FL 33136, USA., Song M; Duke Transplant Center, Department of Surgery, Duke University School of Medicine; Durham, NC 27710, USA., Ladowski JM; Duke Transplant Center, Department of Surgery, Duke University School of Medicine; Durham, NC 27710, USA., Kirk AD; Duke Transplant Center, Department of Surgery, Duke University School of Medicine; Durham, NC 27710, USA., Kenyon NS; Diabetes Research Institute, University of Miami, Miami, FL 33136, USA.; Department of Surgery, University of Miami, Miami, FL 33136, USA.; Department of Microbiology and Immunology, University of Miami, Miami, FL 33136, USA.; Department of Biomedical Engineering, University of Miami, Miami, FL 33136, USA. |
| Source: | Science translational medicine [Sci Transl Med] 2023 Aug 30; Vol. 15 (711), pp. eadf6376. Date of Electronic Publication: 2023 Aug 30. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1946-6242 |
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| DOI: | 10.1126/scitranslmed.adf6376 |
