In vivo reduction of RAD51-mediated homologous recombination triggers aging but impairs oncogenesis.
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| Title: | In vivo reduction of RAD51-mediated homologous recombination triggers aging but impairs oncogenesis. |
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| Authors: | Matos-Rodrigues G; Université de Paris, INSERM U1016, UMR 8104 CNRS, Institut Cochin, Equipe Labellisée Ligue Contre le Cancer, Paris, France.; Université de Paris and Université Paris-Saclay, Laboratory of Development of the Gonads, IRCM/IBFJ CEA, UMR Genetic Stability Stem Cells and Radiation, Fontenay aux Roses, France., Barroca V; Université de Paris and Université Paris-Saclay, Inserm, IRCM/IBFJ CEA, UMR Genetic Stability Stem Cells and Radiation, Fontenay aux Roses, France., Muhammad AA; Genome Maintenance and Molecular Microscopy UMR8126 CNRS, Université Paris-Sud, Université Paris-Saclay, Gustave Roussy, Villejuif Cedex, France., Dardillac E; Université de Paris, INSERM U1016, UMR 8104 CNRS, Institut Cochin, Equipe Labellisée Ligue Contre le Cancer, Paris, France., Allouch A; Cell Death and Aging Team, INSERM U1030, Laboratory of Molecular Radiotherapy, University Paris-Sud and Gustave Roussy, Villejuif, France., Koundrioukoff S; CNRS UMR8200 Sorbonne Universités, UPMC University, Paris, France.; Institut Gustave Roussy, Villejuif, France., Lewandowski D; Université de Paris and Université Paris-Saclay, Inserm, IRCM/IBFJ CEA, UMR Genetic Stability Stem Cells and Radiation, Fontenay aux Roses, France., Despras E; CNRS UMR8200, Laboratory of Genetic Instability and Oncogenesis, University Paris-Sud and Gustave Roussy, Villejuif, France., Guirouilh-Barbat J; Université de Paris, INSERM U1016, UMR 8104 CNRS, Institut Cochin, Equipe Labellisée Ligue Contre le Cancer, Paris, France., Frappart L; Leibniz Institute on Aging-Fritz Lipmann Institute, Jena, Germany., Kannouche P; CNRS UMR8200, Laboratory of Genetic Instability and Oncogenesis, University Paris-Sud and Gustave Roussy, Villejuif, France., Dupaigne P; Genome Maintenance and Molecular Microscopy UMR8126 CNRS, Université Paris-Sud, Université Paris-Saclay, Gustave Roussy, Villejuif Cedex, France., Le Cam E; Genome Maintenance and Molecular Microscopy UMR8126 CNRS, Université Paris-Sud, Université Paris-Saclay, Gustave Roussy, Villejuif Cedex, France., Perfettini JL; Cell Death and Aging Team, INSERM U1030, Laboratory of Molecular Radiotherapy, University Paris-Sud and Gustave Roussy, Villejuif, France., Romeo PH; Université de Paris and Université Paris-Saclay, Inserm, IRCM/IBFJ CEA, UMR Genetic Stability Stem Cells and Radiation, Fontenay aux Roses, France., Debatisse M; CNRS UMR8200 Sorbonne Universités, UPMC University, Paris, France.; Institut Gustave Roussy, Villejuif, France., Jasin M; Developmental Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Livera G; Université de Paris and Université Paris-Saclay, Laboratory of Development of the Gonads, IRCM/IBFJ CEA, UMR Genetic Stability Stem Cells and Radiation, Fontenay aux Roses, France., Martini E; Université de Paris and Université Paris-Saclay, Laboratory of Development of the Gonads, IRCM/IBFJ CEA, UMR Genetic Stability Stem Cells and Radiation, Fontenay aux Roses, France., Lopez BS; Université de Paris, INSERM U1016, UMR 8104 CNRS, Institut Cochin, Equipe Labellisée Ligue Contre le Cancer, Paris, France. |
| Source: | The EMBO journal [EMBO J] 2023 Oct 16; Vol. 42 (20), pp. e110844. Date of Electronic Publication: 2023 Sep 04. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1460-2075 |
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| DOI: | 10.15252/embj.2022110844 |
