Co-administration of an effector antibody enhances the half-life and therapeutic potential of RNA-encoded nanobodies.

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Title: Co-administration of an effector antibody enhances the half-life and therapeutic potential of RNA-encoded nanobodies.
Authors: Thran M; CureVac SE, 72076, Tübingen, Germany., Pönisch M; CureVac SE, 72076, Tübingen, Germany., Danz H; Department of Infectious Disease and Global Health, Tufts Cummings School of Veterinary Medicine, North Grafton, MA, 01536, USA., Horscroft N; CureVac SE, 72076, Tübingen, Germany., Ichtchenko K; Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, 10016, USA., Tzipori S; Department of Infectious Disease and Global Health, Tufts Cummings School of Veterinary Medicine, North Grafton, MA, 01536, USA., Shoemaker CB; Department of Infectious Disease and Global Health, Tufts Cummings School of Veterinary Medicine, North Grafton, MA, 01536, USA. charles.shoemaker@tufts.edu.
Source: Scientific reports [Sci Rep] 2023 Sep 05; Vol. 13 (1), pp. 14632. Date of Electronic Publication: 2023 Sep 05.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2045-2322
DOI:10.1038/s41598-023-41092-7