A generalizable Cas9/sgRNA prediction model using machine transfer learning with small high-quality datasets.
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| Title: | A generalizable Cas9/sgRNA prediction model using machine transfer learning with small high-quality datasets. |
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| Authors: | Ham DT; Department of Biochemistry, Schulich School of Medicine and Dentistry, London, ON, N6A5C1, Canada., Browne TS; Department of Biochemistry, Schulich School of Medicine and Dentistry, London, ON, N6A5C1, Canada., Banglorewala PN; Department of Biochemistry, Schulich School of Medicine and Dentistry, London, ON, N6A5C1, Canada., Wilson TL; Tesseraqt Optimization Inc, Toronto, ON, Canada., Michael RK; Tesseraqt Optimization Inc, Toronto, ON, Canada., Gloor GB; Department of Biochemistry, Schulich School of Medicine and Dentistry, London, ON, N6A5C1, Canada. ggloor@uwo.ca., Edgell DR; Department of Biochemistry, Schulich School of Medicine and Dentistry, London, ON, N6A5C1, Canada. dedgell@uwo.ca. |
| Source: | Nature communications [Nat Commun] 2023 Sep 07; Vol. 14 (1), pp. 5514. Date of Electronic Publication: 2023 Sep 07. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-023-41143-7 |
