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A generalizable Cas9/sgRNA prediction model using machine transfer learning with small high-quality datasets.

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Title: A generalizable Cas9/sgRNA prediction model using machine transfer learning with small high-quality datasets.
Authors: Ham DT; Department of Biochemistry, Schulich School of Medicine and Dentistry, London, ON, N6A5C1, Canada., Browne TS; Department of Biochemistry, Schulich School of Medicine and Dentistry, London, ON, N6A5C1, Canada., Banglorewala PN; Department of Biochemistry, Schulich School of Medicine and Dentistry, London, ON, N6A5C1, Canada., Wilson TL; Tesseraqt Optimization Inc, Toronto, ON, Canada., Michael RK; Tesseraqt Optimization Inc, Toronto, ON, Canada., Gloor GB; Department of Biochemistry, Schulich School of Medicine and Dentistry, London, ON, N6A5C1, Canada. ggloor@uwo.ca., Edgell DR; Department of Biochemistry, Schulich School of Medicine and Dentistry, London, ON, N6A5C1, Canada. dedgell@uwo.ca.
Source: Nature communications [Nat Commun] 2023 Sep 07; Vol. 14 (1), pp. 5514. Date of Electronic Publication: 2023 Sep 07.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Ham+DT%22">Ham DT</searchLink>; Department of Biochemistry, Schulich School of Medicine and Dentistry, London, ON, N6A5C1, Canada.<br /><searchLink fieldCode="AU" term="%22Browne+TS%22">Browne TS</searchLink>; Department of Biochemistry, Schulich School of Medicine and Dentistry, London, ON, N6A5C1, Canada.<br /><searchLink fieldCode="AU" term="%22Banglorewala+PN%22">Banglorewala PN</searchLink>; Department of Biochemistry, Schulich School of Medicine and Dentistry, London, ON, N6A5C1, Canada.<br /><searchLink fieldCode="AU" term="%22Wilson+TL%22">Wilson TL</searchLink>; Tesseraqt Optimization Inc, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Michael+RK%22">Michael RK</searchLink>; Tesseraqt Optimization Inc, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Gloor+GB%22">Gloor GB</searchLink>; Department of Biochemistry, Schulich School of Medicine and Dentistry, London, ON, N6A5C1, Canada. ggloor@uwo.ca.<br /><searchLink fieldCode="AU" term="%22Edgell+DR%22">Edgell DR</searchLink>; Department of Biochemistry, Schulich School of Medicine and Dentistry, London, ON, N6A5C1, Canada. dedgell@uwo.ca.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2023 Sep 07; Vol. 14 (1), pp. 5514. <i>Date of Electronic Publication: </i>2023 Sep 07.
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        Value: 10.1038/s41467-023-41143-7
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