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A single-nucleotide resolution capillary gel electrophoresis workflow for poly(A) tail characterization in the development of mRNA therapeutics and vaccines.

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Bibliographic Details
Title: A single-nucleotide resolution capillary gel electrophoresis workflow for poly(A) tail characterization in the development of mRNA therapeutics and vaccines.
Authors: Di Grandi D; Protein Biochemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591, USA., Dayeh DM; Protein Biochemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591, USA., Kaur K; Regeneron Genetic Medicines, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591, USA., Chen Y; Regeneron Genetic Medicines, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591, USA., Henderson S; Protein Biochemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591, USA., Moon Y; Protein Biochemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591, USA., Bhowmick A; Regeneron Genetic Medicines, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591, USA., Ihnat PM; Protein Biochemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591, USA., Fu Y; Protein Biochemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591, USA. Electronic address: yue.fu@regeneron.com., Muthusamy K; Protein Biochemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591, USA. Electronic address: kathir.muthusamy@regeneron.com., Palackal N; Protein Biochemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591, USA., Pyles EA; Protein Biochemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591, USA.
Source: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2023 Nov 30; Vol. 236, pp. 115692. Date of Electronic Publication: 2023 Sep 02.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-264X (Electronic) Linking ISSN: 07317085 NLM ISO Abbreviation: J Pharm Biomed Anal Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-264X
DOI:10.1016/j.jpba.2023.115692