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Discovery of Selective Tertiary Amide Inhibitors of Cyclin-Dependent Kinase 2 (CDK2).

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Title: Discovery of Selective Tertiary Amide Inhibitors of Cyclin-Dependent Kinase 2 (CDK2).
Authors: Zeng M; Genentech Inc., South San Francisco, California 94080, United States., Grandner JM; Genentech Inc., South San Francisco, California 94080, United States., Bryan MC; Janssen R&D, 1400 McKean Rd, Spring House, Pennsylvania 19002, United States., Verma V; Genentech Inc., South San Francisco, California 94080, United States., Larouche-Gauthier R; Paraza Pharma Inc., Montreal, QC H4S 2E1, Canada., Leclerc JP; Paraza Pharma Inc., Montreal, QC H4S 2E1, Canada., Zhao L; Paraza Pharma Inc., Montreal, QC H4S 2E1, Canada., Haghshenas P; Paraza Pharma Inc., Montreal, QC H4S 2E1, Canada., Aubert-Nicol S; Paraza Pharma Inc., Montreal, QC H4S 2E1, Canada., Yadav A; Paraza Pharma Inc., Montreal, QC H4S 2E1, Canada., Ashley M; Genentech Inc., South San Francisco, California 94080, United States., Chen JZ; Genentech Inc., South San Francisco, California 94080, United States., Durk M; Genentech Inc., South San Francisco, California 94080, United States., Samy KE; Genentech Inc., South San Francisco, California 94080, United States., Nespi M; Genentech Inc., South San Francisco, California 94080, United States., Levy E; Genentech Inc., South San Francisco, California 94080, United States., Merrick K; Genentech Inc., South San Francisco, California 94080, United States., Moffat JG; Genentech Inc., South San Francisco, California 94080, United States., Murray J; Genentech Inc., South San Francisco, California 94080, United States., Oh A; Genentech Inc., South San Francisco, California 94080, United States., Orr C; Genentech Inc., South San Francisco, California 94080, United States., Segal E; Genentech Inc., South San Francisco, California 94080, United States., Sims J; Genentech Inc., South San Francisco, California 94080, United States., Sneeringer C; Genentech Inc., South San Francisco, California 94080, United States., Prangley M; Genentech Inc., South San Francisco, California 94080, United States., Vartanian S; Genentech Inc., South San Francisco, California 94080, United States., Magnuson S; Genentech Inc., South San Francisco, California 94080, United States., Parr BT; Genentech Inc., South San Francisco, California 94080, United States.
Source: ACS medicinal chemistry letters [ACS Med Chem Lett] 2023 Aug 24; Vol. 14 (9), pp. 1179-1187. Date of Electronic Publication: 2023 Aug 24 (Print Publication: 2023).
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Discovery of Selective Tertiary Amide Inhibitors of Cyclin-Dependent Kinase 2 (CDK2).
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  Data: <searchLink fieldCode="AU" term="%22Zeng+M%22">Zeng M</searchLink>; Genentech Inc., South San Francisco, California 94080, United States.<br /><searchLink fieldCode="AU" term="%22Grandner+JM%22">Grandner JM</searchLink>; Genentech Inc., South San Francisco, California 94080, United States.<br /><searchLink fieldCode="AU" term="%22Bryan+MC%22">Bryan MC</searchLink>; Janssen R&D, 1400 McKean Rd, Spring House, Pennsylvania 19002, United States.<br /><searchLink fieldCode="AU" term="%22Verma+V%22">Verma V</searchLink>; Genentech Inc., South San Francisco, California 94080, United States.<br /><searchLink fieldCode="AU" term="%22Larouche-Gauthier+R%22">Larouche-Gauthier R</searchLink>; Paraza Pharma Inc., Montreal, QC H4S 2E1, Canada.<br /><searchLink fieldCode="AU" term="%22Leclerc+JP%22">Leclerc JP</searchLink>; Paraza Pharma Inc., Montreal, QC H4S 2E1, Canada.<br /><searchLink fieldCode="AU" term="%22Zhao+L%22">Zhao L</searchLink>; Paraza Pharma Inc., Montreal, QC H4S 2E1, Canada.<br /><searchLink fieldCode="AU" term="%22Haghshenas+P%22">Haghshenas P</searchLink>; Paraza Pharma Inc., Montreal, QC H4S 2E1, Canada.<br /><searchLink fieldCode="AU" term="%22Aubert-Nicol+S%22">Aubert-Nicol S</searchLink>; Paraza Pharma Inc., Montreal, QC H4S 2E1, Canada.<br /><searchLink fieldCode="AU" term="%22Yadav+A%22">Yadav A</searchLink>; Paraza Pharma Inc., Montreal, QC H4S 2E1, Canada.<br /><searchLink fieldCode="AU" term="%22Ashley+M%22">Ashley M</searchLink>; Genentech Inc., South San Francisco, California 94080, United States.<br /><searchLink fieldCode="AU" term="%22Chen+JZ%22">Chen JZ</searchLink>; Genentech Inc., South San Francisco, California 94080, United States.<br /><searchLink fieldCode="AU" term="%22Durk+M%22">Durk M</searchLink>; Genentech Inc., South San Francisco, California 94080, United States.<br /><searchLink fieldCode="AU" term="%22Samy+KE%22">Samy KE</searchLink>; Genentech Inc., South San Francisco, California 94080, United States.<br /><searchLink fieldCode="AU" term="%22Nespi+M%22">Nespi M</searchLink>; Genentech Inc., South San Francisco, California 94080, United States.<br /><searchLink fieldCode="AU" term="%22Levy+E%22">Levy E</searchLink>; Genentech Inc., South San Francisco, California 94080, United States.<br /><searchLink fieldCode="AU" term="%22Merrick+K%22">Merrick K</searchLink>; Genentech Inc., South San Francisco, California 94080, United States.<br /><searchLink fieldCode="AU" term="%22Moffat+JG%22">Moffat JG</searchLink>; Genentech Inc., South San Francisco, California 94080, United States.<br /><searchLink fieldCode="AU" term="%22Murray+J%22">Murray J</searchLink>; Genentech Inc., South San Francisco, California 94080, United States.<br /><searchLink fieldCode="AU" term="%22Oh+A%22">Oh A</searchLink>; Genentech Inc., South San Francisco, California 94080, United States.<br /><searchLink fieldCode="AU" term="%22Orr+C%22">Orr C</searchLink>; Genentech Inc., South San Francisco, California 94080, United States.<br /><searchLink fieldCode="AU" term="%22Segal+E%22">Segal E</searchLink>; Genentech Inc., South San Francisco, California 94080, United States.<br /><searchLink fieldCode="AU" term="%22Sims+J%22">Sims J</searchLink>; Genentech Inc., South San Francisco, California 94080, United States.<br /><searchLink fieldCode="AU" term="%22Sneeringer+C%22">Sneeringer C</searchLink>; Genentech Inc., South San Francisco, California 94080, United States.<br /><searchLink fieldCode="AU" term="%22Prangley+M%22">Prangley M</searchLink>; Genentech Inc., South San Francisco, California 94080, United States.<br /><searchLink fieldCode="AU" term="%22Vartanian+S%22">Vartanian S</searchLink>; Genentech Inc., South San Francisco, California 94080, United States.<br /><searchLink fieldCode="AU" term="%22Magnuson+S%22">Magnuson S</searchLink>; Genentech Inc., South San Francisco, California 94080, United States.<br /><searchLink fieldCode="AU" term="%22Parr+BT%22">Parr BT</searchLink>; Genentech Inc., South San Francisco, California 94080, United States.
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