Targetable NOTCH1 rearrangements in reninoma.

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Title: Targetable NOTCH1 rearrangements in reninoma.
Authors: Treger TD; Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.; Department of Paediatrics, University of Cambridge, Cambridge, CB2 0QQ, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ, UK., Lawrence JEG; Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ, UK., Anderson ND; Wellcome Sanger Institute, Hinxton, CB10 1SA, UK., Coorens THH; Broad Institute of MIT and Harvard, Cambridge, 02142 MA, USA., Letunovska A; UCL Great Ormond Street Institute of Child Health, London, WC1N 1EH, UK.; NIHR Great Ormond Street Hospital Biomedical Research Centre, London, WC1N 3JH, UK., Abby E; Wellcome Sanger Institute, Hinxton, CB10 1SA, UK., Lee-Six H; Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.; Department of Pathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ, UK., Oliver TRW; Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.; Department of Pathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ, UK., Al-Saadi R; UCL Great Ormond Street Institute of Child Health, London, WC1N 1EH, UK.; NIHR Great Ormond Street Hospital Biomedical Research Centre, London, WC1N 3JH, UK., Tullus K; UCL Great Ormond Street Institute of Child Health, London, WC1N 1EH, UK.; NIHR Great Ormond Street Hospital Biomedical Research Centre, London, WC1N 3JH, UK., Morcrette G; UCL Great Ormond Street Institute of Child Health, London, WC1N 1EH, UK.; NIHR Great Ormond Street Hospital Biomedical Research Centre, London, WC1N 3JH, UK., Hutchinson JC; NIHR Great Ormond Street Hospital Biomedical Research Centre, London, WC1N 3JH, UK., Rampling D; NIHR Great Ormond Street Hospital Biomedical Research Centre, London, WC1N 3JH, UK., Sebire N; UCL Great Ormond Street Institute of Child Health, London, WC1N 1EH, UK.; NIHR Great Ormond Street Hospital Biomedical Research Centre, London, WC1N 3JH, UK., Pritchard-Jones K; UCL Great Ormond Street Institute of Child Health, London, WC1N 1EH, UK., Young MD; Wellcome Sanger Institute, Hinxton, CB10 1SA, UK., Mitchell TJ; Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ, UK.; Early Cancer Institute, University of Cambridge, Cambridge, CB2 0XZ, UK., Jones PH; Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.; Department of Oncology, University of Cambridge, Cambridge, CB2 OXZ, UK., Tran M; Specialist Centre for Kidney Cancer, Royal Free Hospital, London, NW3 2QG, UK. m.tran@ucl.ac.uk.; Faculty of Medical Sciences, Division of Surgery and Interventional Science, University College London, London, NW3 2PS, UK. m.tran@ucl.ac.uk., Behjati S; Wellcome Sanger Institute, Hinxton, CB10 1SA, UK. sb31@sanger.ac.uk.; Department of Paediatrics, University of Cambridge, Cambridge, CB2 0QQ, UK. sb31@sanger.ac.uk.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ, UK. sb31@sanger.ac.uk., Chowdhury T; UCL Great Ormond Street Institute of Child Health, London, WC1N 1EH, UK. Tanzina.Chowdhury@gosh.nhs.uk.; NIHR Great Ormond Street Hospital Biomedical Research Centre, London, WC1N 3JH, UK. Tanzina.Chowdhury@gosh.nhs.uk.
Source: Nature communications [Nat Commun] 2023 Sep 25; Vol. 14 (1), pp. 5826. Date of Electronic Publication: 2023 Sep 25.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Targetable NOTCH1 rearrangements in reninoma.
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  Data: <searchLink fieldCode="AU" term="%22Treger+TD%22">Treger TD</searchLink>; Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.; Department of Paediatrics, University of Cambridge, Cambridge, CB2 0QQ, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ, UK.<br /><searchLink fieldCode="AU" term="%22Lawrence+JEG%22">Lawrence JEG</searchLink>; Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ, UK.<br /><searchLink fieldCode="AU" term="%22Anderson+ND%22">Anderson ND</searchLink>; Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.<br /><searchLink fieldCode="AU" term="%22Coorens+THH%22">Coorens THH</searchLink>; Broad Institute of MIT and Harvard, Cambridge, 02142 MA, USA.<br /><searchLink fieldCode="AU" term="%22Letunovska+A%22">Letunovska A</searchLink>; UCL Great Ormond Street Institute of Child Health, London, WC1N 1EH, UK.; NIHR Great Ormond Street Hospital Biomedical Research Centre, London, WC1N 3JH, UK.<br /><searchLink fieldCode="AU" term="%22Abby+E%22">Abby E</searchLink>; Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.<br /><searchLink fieldCode="AU" term="%22Lee-Six+H%22">Lee-Six H</searchLink>; Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.; Department of Pathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ, UK.<br /><searchLink fieldCode="AU" term="%22Oliver+TRW%22">Oliver TRW</searchLink>; Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.; Department of Pathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ, UK.<br /><searchLink fieldCode="AU" term="%22Al-Saadi+R%22">Al-Saadi R</searchLink>; UCL Great Ormond Street Institute of Child Health, London, WC1N 1EH, UK.; NIHR Great Ormond Street Hospital Biomedical Research Centre, London, WC1N 3JH, UK.<br /><searchLink fieldCode="AU" term="%22Tullus+K%22">Tullus K</searchLink>; UCL Great Ormond Street Institute of Child Health, London, WC1N 1EH, UK.; NIHR Great Ormond Street Hospital Biomedical Research Centre, London, WC1N 3JH, UK.<br /><searchLink fieldCode="AU" term="%22Morcrette+G%22">Morcrette G</searchLink>; UCL Great Ormond Street Institute of Child Health, London, WC1N 1EH, UK.; NIHR Great Ormond Street Hospital Biomedical Research Centre, London, WC1N 3JH, UK.<br /><searchLink fieldCode="AU" term="%22Hutchinson+JC%22">Hutchinson JC</searchLink>; NIHR Great Ormond Street Hospital Biomedical Research Centre, London, WC1N 3JH, UK.<br /><searchLink fieldCode="AU" term="%22Rampling+D%22">Rampling D</searchLink>; NIHR Great Ormond Street Hospital Biomedical Research Centre, London, WC1N 3JH, UK.<br /><searchLink fieldCode="AU" term="%22Sebire+N%22">Sebire N</searchLink>; UCL Great Ormond Street Institute of Child Health, London, WC1N 1EH, UK.; NIHR Great Ormond Street Hospital Biomedical Research Centre, London, WC1N 3JH, UK.<br /><searchLink fieldCode="AU" term="%22Pritchard-Jones+K%22">Pritchard-Jones K</searchLink>; UCL Great Ormond Street Institute of Child Health, London, WC1N 1EH, UK.<br /><searchLink fieldCode="AU" term="%22Young+MD%22">Young MD</searchLink>; Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.<br /><searchLink fieldCode="AU" term="%22Mitchell+TJ%22">Mitchell TJ</searchLink>; Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ, UK.; Early Cancer Institute, University of Cambridge, Cambridge, CB2 0XZ, UK.<br /><searchLink fieldCode="AU" term="%22Jones+PH%22">Jones PH</searchLink>; Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.; Department of Oncology, University of Cambridge, Cambridge, CB2 OXZ, UK.<br /><searchLink fieldCode="AU" term="%22Tran+M%22">Tran M</searchLink>; Specialist Centre for Kidney Cancer, Royal Free Hospital, London, NW3 2QG, UK. m.tran@ucl.ac.uk.; Faculty of Medical Sciences, Division of Surgery and Interventional Science, University College London, London, NW3 2PS, UK. m.tran@ucl.ac.uk.<br /><searchLink fieldCode="AU" term="%22Behjati+S%22">Behjati S</searchLink>; Wellcome Sanger Institute, Hinxton, CB10 1SA, UK. sb31@sanger.ac.uk.; Department of Paediatrics, University of Cambridge, Cambridge, CB2 0QQ, UK. sb31@sanger.ac.uk.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ, UK. sb31@sanger.ac.uk.<br /><searchLink fieldCode="AU" term="%22Chowdhury+T%22">Chowdhury T</searchLink>; UCL Great Ormond Street Institute of Child Health, London, WC1N 1EH, UK. Tanzina.Chowdhury@gosh.nhs.uk.; NIHR Great Ormond Street Hospital Biomedical Research Centre, London, WC1N 3JH, UK. Tanzina.Chowdhury@gosh.nhs.uk.
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