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Targeting ryanodine receptor type 2 to mitigate chemotherapy-induced neurocognitive impairments in mice.

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Title: Targeting ryanodine receptor type 2 to mitigate chemotherapy-induced neurocognitive impairments in mice.
Authors: Liu Y; Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY 10032, USA., Reiken S; Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY 10032, USA., Dridi H; Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY 10032, USA., Yuan Q; Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY 10032, USA., Mohammad KS; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Present address: College of Medicine, Alfaisal University, Box 50927, Riyadh 1153, Kingdom of Saudi Arabia., Trivedi T; Department of Endocrine Neoplasia and Hormonal Disorders, Division of Internal Medicine, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Miotto MC; Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY 10032, USA., Wedderburn-Pugh K; Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY 10032, USA., Sittenfeld L; Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY 10032, USA., Kerley Y; Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY 10032, USA., Meyer JA; Stark Neuroscience Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Peters JS; Stark Neuroscience Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Persohn SC; Stark Neuroscience Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Bedwell AA; Stark Neuroscience Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Figueiredo LL; Stark Neuroscience Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Suresh S; Department of Endocrine Neoplasia and Hormonal Disorders, Division of Internal Medicine, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., She Y; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Soni RK; Proteomics and Macromolecular Crystallography Shared Resource, Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY 10032, USA., Territo PR; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Stark Neuroscience Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Marks AR; Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY 10032, USA., Guise TA; Department of Endocrine Neoplasia and Hormonal Disorders, Division of Internal Medicine, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Source: Science translational medicine [Sci Transl Med] 2023 Sep 27; Vol. 15 (715), pp. eadf8977. Date of Electronic Publication: 2023 Sep 27.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Targeting ryanodine receptor type 2 to mitigate chemotherapy-induced neurocognitive impairments in mice.
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  Data: <searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Reiken+S%22">Reiken S</searchLink>; Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Dridi+H%22">Dridi H</searchLink>; Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Yuan+Q%22">Yuan Q</searchLink>; Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Mohammad+KS%22">Mohammad KS</searchLink>; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Present address: College of Medicine, Alfaisal University, Box 50927, Riyadh 1153, Kingdom of Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Trivedi+T%22">Trivedi T</searchLink>; Department of Endocrine Neoplasia and Hormonal Disorders, Division of Internal Medicine, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Miotto+MC%22">Miotto MC</searchLink>; Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Wedderburn-Pugh+K%22">Wedderburn-Pugh K</searchLink>; Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Sittenfeld+L%22">Sittenfeld L</searchLink>; Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Kerley+Y%22">Kerley Y</searchLink>; Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Meyer+JA%22">Meyer JA</searchLink>; Stark Neuroscience Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA.<br /><searchLink fieldCode="AU" term="%22Peters+JS%22">Peters JS</searchLink>; Stark Neuroscience Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA.<br /><searchLink fieldCode="AU" term="%22Persohn+SC%22">Persohn SC</searchLink>; Stark Neuroscience Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA.<br /><searchLink fieldCode="AU" term="%22Bedwell+AA%22">Bedwell AA</searchLink>; Stark Neuroscience Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA.<br /><searchLink fieldCode="AU" term="%22Figueiredo+LL%22">Figueiredo LL</searchLink>; Stark Neuroscience Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA.<br /><searchLink fieldCode="AU" term="%22Suresh+S%22">Suresh S</searchLink>; Department of Endocrine Neoplasia and Hormonal Disorders, Division of Internal Medicine, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22She+Y%22">She Y</searchLink>; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.<br /><searchLink fieldCode="AU" term="%22Soni+RK%22">Soni RK</searchLink>; Proteomics and Macromolecular Crystallography Shared Resource, Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Territo+PR%22">Territo PR</searchLink>; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Stark Neuroscience Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA.<br /><searchLink fieldCode="AU" term="%22Marks+AR%22">Marks AR</searchLink>; Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Guise+TA%22">Guise TA</searchLink>; Department of Endocrine Neoplasia and Hormonal Disorders, Division of Internal Medicine, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
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