Distinct SARS-CoV-2 specific NLRP3 and IL-1β responses in T cells of aging patients during acute COVID-19 infection.

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Title: Distinct SARS-CoV-2 specific NLRP3 and IL-1β responses in T cells of aging patients during acute COVID-19 infection.
Authors: Mahalingam SS; Department of Biological Sciences, School of Dental Medicine, Case Western Reserve University, Cleveland, OH, United States., Jayaraman S; Department of Biological Sciences, School of Dental Medicine, Case Western Reserve University, Cleveland, OH, United States., Arunkumar A; Department of Biological Sciences, School of Dental Medicine, Case Western Reserve University, Cleveland, OH, United States., Dudley HM; Department of Molecular Biology and Microbiology, School of Medicine, Case Western Reserve University, Cleveland, OH, United States., Anthony DD; Department of Rheumatology, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH, United States.; Department of Pathology, Case Western Reserve University, Cleveland, OH, United States.; Center for AIDS Research, School of Medicine, Case Western Reserve University, Cleveland, OH, United States.; Department of Medicine, School of Medicine, University Hospitals, Case Western Reserve University, Cleveland, OH, United States., Shive CL; Department of Rheumatology, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH, United States.; Department of Pathology, Case Western Reserve University, Cleveland, OH, United States., Jacobson JM; Center for AIDS Research, School of Medicine, Case Western Reserve University, Cleveland, OH, United States.; Department of Medicine, School of Medicine, University Hospitals, Case Western Reserve University, Cleveland, OH, United States., Pandiyan P; Department of Biological Sciences, School of Dental Medicine, Case Western Reserve University, Cleveland, OH, United States.; Department of Rheumatology, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH, United States.; Center for AIDS Research, School of Medicine, Case Western Reserve University, Cleveland, OH, United States.
Source: Frontiers in immunology [Front Immunol] 2023 Sep 18; Vol. 14, pp. 1231087. Date of Electronic Publication: 2023 Sep 18 (Print Publication: 2023).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1664-3224
DOI:10.3389/fimmu.2023.1231087