Systematic functional interrogation of SARS-CoV-2 host factors using Perturb-seq.
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| Title: | Systematic functional interrogation of SARS-CoV-2 host factors using Perturb-seq. |
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| Authors: | Sunshine S; Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA., Puschnik AS; Chan Zuckerberg Biohub, San Francisco, San Francisco, CA, USA., Replogle JM; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA.; Whitehead Institute for Biomedical Research, Cambridge, MA, USA., Laurie MT; Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA., Liu J; Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA.; University of California, Berkeley-UCSF Joint Graduate Program in Bioengineering, San Francisco, CA, USA., Zha BS; Department of Medicine, Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, San Francisco, CA, USA., Nuñez JK; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA.; Department of Molecular & Cell Biology, University of California, Berkeley, Berkeley, CA, USA., Byrum JR; Chan Zuckerberg Biohub, San Francisco, San Francisco, CA, USA., McMorrow AH; Chan Zuckerberg Biohub, San Francisco, San Francisco, CA, USA., Frieman MB; Department of Microbiology and Immunology, Center for Pathogen Research, University of Maryland School of Medicine, Baltimore, MD, USA., Winkler J; Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, CA, USA.; Center for Cancer Research, Medical University of Vienna, Vienna, Austria., Qiu X; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, USA., Rosenberg OS; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA., Leonetti MD; Chan Zuckerberg Biohub, San Francisco, San Francisco, CA, USA., Ye CJ; Division of Rheumatology, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.; Institute of Human Genetics, University of California San Francisco, San Francisco, CA, USA.; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA.; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA., Weissman JS; Whitehead Institute for Biomedical Research, Cambridge, MA, USA. weissman@wi.mit.edu.; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, USA. weissman@wi.mit.edu.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA. weissman@wi.mit.edu.; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA. weissman@wi.mit.edu., DeRisi JL; Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA. joe@derisilab.ucsf.edu.; Chan Zuckerberg Biohub, San Francisco, San Francisco, CA, USA. joe@derisilab.ucsf.edu., Hein MY; Chan Zuckerberg Biohub, San Francisco, San Francisco, CA, USA. marco.hein@maxperutzlabs.ac.at.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA. marco.hein@maxperutzlabs.ac.at.; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA. marco.hein@maxperutzlabs.ac.at.; Max Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, Austria. marco.hein@maxperutzlabs.ac.at.; Medical University of Vienna, Center for Medical Biochemistry, Vienna, Austria. marco.hein@maxperutzlabs.ac.at. |
| Source: | Nature communications [Nat Commun] 2023 Oct 06; Vol. 14 (1), pp. 6245. Date of Electronic Publication: 2023 Oct 06. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-023-41788-4 |
