Antisense oligonucleotides restore excitability, GABA signalling and sodium current density in a Dravet syndrome model.
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| Title: | Antisense oligonucleotides restore excitability, GABA signalling and sodium current density in a Dravet syndrome model. |
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| Authors: | Yuan Y; Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109, USA., Lopez-Santiago L; Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109, USA., Denomme N; Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109, USA., Chen C; Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109, USA., O'Malley HA; Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109, USA., Hodges SL; Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109, USA., Ji S; Stoke Therapeutics, Inc., Bedford, MA 01730, USA., Han Z; Stoke Therapeutics, Inc., Bedford, MA 01730, USA., Christiansen A; Stoke Therapeutics, Inc., Bedford, MA 01730, USA., Isom LL; Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109, USA. |
| Source: | Brain : a journal of neurology [Brain] 2024 Apr 04; Vol. 147 (4), pp. 1231-1246. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1460-2156 |
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| DOI: | 10.1093/brain/awad349 |