Efficacy and safety of ivermectin for the treatment of Plasmodium falciparum infections in asymptomatic male and female Gabonese adults - a pilot randomized, double-blind, placebo-controlled single-centre phase Ib/IIa clinical trial.
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| Title: | Efficacy and safety of ivermectin for the treatment of Plasmodium falciparum infections in asymptomatic male and female Gabonese adults - a pilot randomized, double-blind, placebo-controlled single-centre phase Ib/IIa clinical trial. |
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| Authors: | Ekoka Mbassi D; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon; Centre for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine & I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; German Center for Infection Research (DZIF), Partner Site Hamburg-Borstel-Lübeck-Riems, Germany., Mombo-Ngoma G; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon; German Center for Infection Research (DZIF), Partner Site Hamburg-Borstel-Lübeck-Riems, Germany; Department of Implementation Research, Bernhard Nocht Institute for Tropical Medicine & I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Held J; Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany; German Center for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany., Okwu DG; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon; Department of Implementation Research, Bernhard Nocht Institute for Tropical Medicine & I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Ndzebe-Ndoumba W; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon; Department of Implementation Research, Bernhard Nocht Institute for Tropical Medicine & I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Kalkman LC; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon., Ekoka Mbassi FA; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon; Centre for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine & I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; German Center for Infection Research (DZIF), Partner Site Hamburg-Borstel-Lübeck-Riems, Germany., Pessanha de Carvalho L; Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany., Inoue J; Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany., Akinosho MA; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon., Dimessa Mbadinga LB; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon., Yovo EK; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon., Mordmüller B; Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany; Department of Medical Microbiology, Radboud University Medical Centre, Nijmegen, the Netherlands., Kremsner PG; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon; Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany; German Center for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany., Adegnika AA; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon; Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany; German Center for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany; Department of Parasitology, Leiden University Medical Centre (LUMC), 2333 ZA, Leiden, the Netherlands; Fondation pour la Recherche Scientifique, 72 BP45, Cotonou, Benin., Ramharter M; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon; Centre for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine & I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; German Center for Infection Research (DZIF), Partner Site Hamburg-Borstel-Lübeck-Riems, Germany., Zoleko-Manego R; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon; Centre for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine & I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; German Center for Infection Research (DZIF), Partner Site Hamburg-Borstel-Lübeck-Riems, Germany; Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany. Electronic address: rella.zoleko-manego@bnitm.de. |
| Source: | EBioMedicine [EBioMedicine] 2023 Nov; Vol. 97, pp. 104814. Date of Electronic Publication: 2023 Oct 13. |
| Publication Type: | Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial |
| Journal Info: | Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101647039 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3964 (Electronic) Linking ISSN: 23523964 NLM ISO Abbreviation: EBioMedicine Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 37839134 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Efficacy and safety of ivermectin for the treatment of Plasmodium falciparum infections in asymptomatic male and female Gabonese adults - a pilot randomized, double-blind, placebo-controlled single-centre phase Ib/IIa clinical trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Ekoka+Mbassi+D%22">Ekoka Mbassi D</searchLink>; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon; Centre for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine & I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; German Center for Infection Research (DZIF), Partner Site Hamburg-Borstel-Lübeck-Riems, Germany.<br /><searchLink fieldCode="AU" term="%22Mombo-Ngoma+G%22">Mombo-Ngoma G</searchLink>; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon; German Center for Infection Research (DZIF), Partner Site Hamburg-Borstel-Lübeck-Riems, Germany; Department of Implementation Research, Bernhard Nocht Institute for Tropical Medicine & I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Held+J%22">Held J</searchLink>; Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany; German Center for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Okwu+DG%22">Okwu DG</searchLink>; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon; Department of Implementation Research, Bernhard Nocht Institute for Tropical Medicine & I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Ndzebe-Ndoumba+W%22">Ndzebe-Ndoumba W</searchLink>; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon; Department of Implementation Research, Bernhard Nocht Institute for Tropical Medicine & I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Kalkman+LC%22">Kalkman LC</searchLink>; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.<br /><searchLink fieldCode="AU" term="%22Ekoka+Mbassi+FA%22">Ekoka Mbassi FA</searchLink>; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon; Centre for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine & I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; German Center for Infection Research (DZIF), Partner Site Hamburg-Borstel-Lübeck-Riems, Germany.<br /><searchLink fieldCode="AU" term="%22Pessanha+de+Carvalho+L%22">Pessanha de Carvalho L</searchLink>; Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Inoue+J%22">Inoue J</searchLink>; Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Akinosho+MA%22">Akinosho MA</searchLink>; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.<br /><searchLink fieldCode="AU" term="%22Dimessa+Mbadinga+LB%22">Dimessa Mbadinga LB</searchLink>; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.<br /><searchLink fieldCode="AU" term="%22Yovo+EK%22">Yovo EK</searchLink>; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.<br /><searchLink fieldCode="AU" term="%22Mordmüller+B%22">Mordmüller B</searchLink>; Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany; Department of Medical Microbiology, Radboud University Medical Centre, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Kremsner+PG%22">Kremsner PG</searchLink>; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon; Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany; German Center for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Adegnika+AA%22">Adegnika AA</searchLink>; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon; Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany; German Center for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany; Department of Parasitology, Leiden University Medical Centre (LUMC), 2333 ZA, Leiden, the Netherlands; Fondation pour la Recherche Scientifique, 72 BP45, Cotonou, Benin.<br /><searchLink fieldCode="AU" term="%22Ramharter+M%22">Ramharter M</searchLink>; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon; Centre for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine & I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; German Center for Infection Research (DZIF), Partner Site Hamburg-Borstel-Lübeck-Riems, Germany.<br /><searchLink fieldCode="AU" term="%22Zoleko-Manego+R%22">Zoleko-Manego R</searchLink>; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon; Centre for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine & I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; German Center for Infection Research (DZIF), Partner Site Hamburg-Borstel-Lübeck-Riems, Germany; Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany. Electronic address: rella.zoleko-manego@bnitm.de. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101647039%22">EBioMedicine</searchLink> [EBioMedicine] 2023 Nov; Vol. 97, pp. 104814. <i>Date of Electronic Publication: </i>2023 Oct 13. – Name: TypePub Label: Publication Type Group: TypPub Data: Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+B%2EV%22">Elsevier B.V </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101647039 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2352-3964 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223523964%22">23523964 </searchLink><i>NLM ISO Abbreviation: </i>EBioMedicine <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=37839134 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.ebiom.2023.104814 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 104814 Titles: – TitleFull: Efficacy and safety of ivermectin for the treatment of Plasmodium falciparum infections in asymptomatic male and female Gabonese adults - a pilot randomized, double-blind, placebo-controlled single-centre phase Ib/IIa clinical trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Ekoka Mbassi D – PersonEntity: Name: NameFull: Mombo-Ngoma G – PersonEntity: Name: NameFull: Held J – PersonEntity: Name: NameFull: Okwu DG – PersonEntity: Name: NameFull: Ndzebe-Ndoumba W – PersonEntity: Name: NameFull: Kalkman LC – PersonEntity: Name: NameFull: Ekoka Mbassi FA – PersonEntity: Name: NameFull: Pessanha de Carvalho L – PersonEntity: Name: NameFull: Inoue J – PersonEntity: Name: NameFull: Akinosho MA – PersonEntity: Name: NameFull: Dimessa Mbadinga LB – PersonEntity: Name: NameFull: Yovo EK – PersonEntity: Name: NameFull: Mordmüller B – PersonEntity: Name: NameFull: Kremsner PG – PersonEntity: Name: NameFull: Adegnika AA – PersonEntity: Name: NameFull: Ramharter M – PersonEntity: Name: NameFull: Zoleko-Manego R IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 11 Text: 2023 Nov Type: published Y: 2023 Identifiers: – Type: issn-electronic Value: 2352-3964 Numbering: – Type: volume Value: 97 Titles: – TitleFull: EBioMedicine Type: main |
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