Inactive S. aureus Cas9 downregulates alpha-synuclein and reduces mtDNA damage and oxidative stress levels in human stem cell model of Parkinson's disease.
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| Title: | Inactive S. aureus Cas9 downregulates alpha-synuclein and reduces mtDNA damage and oxidative stress levels in human stem cell model of Parkinson's disease. |
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| Authors: | Sastre D; Department of Pathology, Stanford University School of Medicine, 300 Pasteur Dr., R271/217, Stanford, CA, 94305, USA., Zafar F; Department of Pathology, Stanford University School of Medicine, 300 Pasteur Dr., R271/217, Stanford, CA, 94305, USA., Torres CAM; Department of Pathology, Stanford University School of Medicine, 300 Pasteur Dr., R271/217, Stanford, CA, 94305, USA., Piper D; Department of Biological Sciences, San Jose State University, San Jose, CA, 95192, USA., Kirik D; Department of Experimental Medical Science, Lund University, Lund, Sweden., Sanders LH; Departments of Neurology and Pathology, Duke Center for Neurodegeneration and Neurotherapeutics, Duke University Medical Center, Durham, NC, 27710, USA., Qi LS; Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA., Schüle B; Department of Pathology, Stanford University School of Medicine, 300 Pasteur Dr., R271/217, Stanford, CA, 94305, USA. bschuele@stanford.edu.; Biosciences Division, SRI International, Menlo Park, CA, 94025, USA. bschuele@stanford.edu. |
| Source: | Scientific reports [Sci Rep] 2023 Oct 18; Vol. 13 (1), pp. 17796. Date of Electronic Publication: 2023 Oct 18. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 37853101 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Inactive S. aureus Cas9 downregulates alpha-synuclein and reduces mtDNA damage and oxidative stress levels in human stem cell model of Parkinson's disease. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Sastre+D%22">Sastre D</searchLink>; Department of Pathology, Stanford University School of Medicine, 300 Pasteur Dr., R271/217, Stanford, CA, 94305, USA.<br /><searchLink fieldCode="AU" term="%22Zafar+F%22">Zafar F</searchLink>; Department of Pathology, Stanford University School of Medicine, 300 Pasteur Dr., R271/217, Stanford, CA, 94305, USA.<br /><searchLink fieldCode="AU" term="%22Torres+CAM%22">Torres CAM</searchLink>; Department of Pathology, Stanford University School of Medicine, 300 Pasteur Dr., R271/217, Stanford, CA, 94305, USA.<br /><searchLink fieldCode="AU" term="%22Piper+D%22">Piper D</searchLink>; Department of Biological Sciences, San Jose State University, San Jose, CA, 95192, USA.<br /><searchLink fieldCode="AU" term="%22Kirik+D%22">Kirik D</searchLink>; Department of Experimental Medical Science, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Sanders+LH%22">Sanders LH</searchLink>; Departments of Neurology and Pathology, Duke Center for Neurodegeneration and Neurotherapeutics, Duke University Medical Center, Durham, NC, 27710, USA.<br /><searchLink fieldCode="AU" term="%22Qi+LS%22">Qi LS</searchLink>; Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA.<br /><searchLink fieldCode="AU" term="%22Schüle+B%22">Schüle B</searchLink>; Department of Pathology, Stanford University School of Medicine, 300 Pasteur Dr., R271/217, Stanford, CA, 94305, USA. bschuele@stanford.edu.; Biosciences Division, SRI International, Menlo Park, CA, 94025, USA. bschuele@stanford.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2023 Oct 18; Vol. 13 (1), pp. 17796. <i>Date of Electronic Publication: </i>2023 Oct 18. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101563288 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2045-2322 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220452322%22">20452322 </searchLink><i>NLM ISO Abbreviation: </i>Sci Rep <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=37853101 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41598-023-45078-3 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 17796 Titles: – TitleFull: Inactive S. aureus Cas9 downregulates alpha-synuclein and reduces mtDNA damage and oxidative stress levels in human stem cell model of Parkinson's disease. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Sastre D – PersonEntity: Name: NameFull: Zafar F – PersonEntity: Name: NameFull: Torres CAM – PersonEntity: Name: NameFull: Piper D – PersonEntity: Name: NameFull: Kirik D – PersonEntity: Name: NameFull: Sanders LH – PersonEntity: Name: NameFull: Qi LS – PersonEntity: Name: NameFull: Schüle B IsPartOfRelationships: – BibEntity: Dates: – D: 18 M: 10 Text: 2023 Oct 18 Type: published Y: 2023 Identifiers: – Type: issn-electronic Value: 2045-2322 Numbering: – Type: volume Value: 13 – Type: issue Value: 1 Titles: – TitleFull: Scientific reports Type: main |
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