Repurposing conformational changes in ANL superfamily enzymes to rapidly generate biosensors for organic and amino acids.

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Title: Repurposing conformational changes in ANL superfamily enzymes to rapidly generate biosensors for organic and amino acids.
Authors: Wang J; University of Chinese Academy of Sciences, 100049, Beijing, China.; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, 300308, Tianjin, China.; Haihe Laboratory of Synthetic Biology, 300308, Tianjin, China.; Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, 300308, Tianjin, China., Xue N; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, 300308, Tianjin, China.; Haihe Laboratory of Synthetic Biology, 300308, Tianjin, China.; Tianjin University of Science & Technology, 300457, Tianjin, China., Pan W; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, 300308, Tianjin, China.; Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, 300308, Tianjin, China., Tu R; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, 300308, Tianjin, China.; College of Environmental and Resources, Chongqing Technology and Business University, 400067, Chongqing, China., Li S; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, 300308, Tianjin, China.; Tianjin University of Science & Technology, 300457, Tianjin, China., Zhang Y; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, 300308, Tianjin, China.; Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, 300308, Tianjin, China., Mao Y; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, 300308, Tianjin, China.; Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, 300308, Tianjin, China., Liu Y; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, 300308, Tianjin, China.; Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, 300308, Tianjin, China., Cheng H; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, 300308, Tianjin, China.; Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, 300308, Tianjin, China., Guo Y; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, 300308, Tianjin, China.; Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, 300308, Tianjin, China., Yuan W; University of Chinese Academy of Sciences, 100049, Beijing, China.; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, 300308, Tianjin, China.; Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, 300308, Tianjin, China., Ni X; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, 300308, Tianjin, China., Wang M; University of Chinese Academy of Sciences, 100049, Beijing, China. wangmeng@tib.cas.cn.; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, 300308, Tianjin, China. wangmeng@tib.cas.cn.; Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, 300308, Tianjin, China. wangmeng@tib.cas.cn.
Source: Nature communications [Nat Commun] 2023 Oct 21; Vol. 14 (1), pp. 6680. Date of Electronic Publication: 2023 Oct 21.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-023-42431-y