Gadolinium-based Contrast Agent Biodistribution and Speciation in Rats.

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Title: Gadolinium-based Contrast Agent Biodistribution and Speciation in Rats.
Authors: Le Fur M; From the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., D.I.G., P.C.), Department of Urology (A.S.F.), and Department of Pathology (I.A.R., I.D.A.L.H., L.P.H.), Massachusetts General Hospital and Harvard Medical School, 149 13th St, Charlestown, MA 02129; Institute for Innovation in Imaging, Massachusetts General Hospital, Charlestown, Mass (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., P.C.); Harvard-MIT Health Sciences and Technology, Cambridge, Mass (D.I.G.); Bioengineering Department, Universidad Carlos III de Madrid, Madrid, Spain (D.I.G.); Department of Chemistry and Biochemistry, University of Arizona, Tucson, Ariz (A.V.A.); and Trace Element Analysis Laboratory, Dartmouth College, Hanover, NH (B.P.J.)., Moon BF; From the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., D.I.G., P.C.), Department of Urology (A.S.F.), and Department of Pathology (I.A.R., I.D.A.L.H., L.P.H.), Massachusetts General Hospital and Harvard Medical School, 149 13th St, Charlestown, MA 02129; Institute for Innovation in Imaging, Massachusetts General Hospital, Charlestown, Mass (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., P.C.); Harvard-MIT Health Sciences and Technology, Cambridge, Mass (D.I.G.); Bioengineering Department, Universidad Carlos III de Madrid, Madrid, Spain (D.I.G.); Department of Chemistry and Biochemistry, University of Arizona, Tucson, Ariz (A.V.A.); and Trace Element Analysis Laboratory, Dartmouth College, Hanover, NH (B.P.J.)., Zhou IY; From the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., D.I.G., P.C.), Department of Urology (A.S.F.), and Department of Pathology (I.A.R., I.D.A.L.H., L.P.H.), Massachusetts General Hospital and Harvard Medical School, 149 13th St, Charlestown, MA 02129; Institute for Innovation in Imaging, Massachusetts General Hospital, Charlestown, Mass (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., P.C.); Harvard-MIT Health Sciences and Technology, Cambridge, Mass (D.I.G.); Bioengineering Department, Universidad Carlos III de Madrid, Madrid, Spain (D.I.G.); Department of Chemistry and Biochemistry, University of Arizona, Tucson, Ariz (A.V.A.); and Trace Element Analysis Laboratory, Dartmouth College, Hanover, NH (B.P.J.)., Zygmont S; From the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., D.I.G., P.C.), Department of Urology (A.S.F.), and Department of Pathology (I.A.R., I.D.A.L.H., L.P.H.), Massachusetts General Hospital and Harvard Medical School, 149 13th St, Charlestown, MA 02129; Institute for Innovation in Imaging, Massachusetts General Hospital, Charlestown, Mass (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., P.C.); Harvard-MIT Health Sciences and Technology, Cambridge, Mass (D.I.G.); Bioengineering Department, Universidad Carlos III de Madrid, Madrid, Spain (D.I.G.); Department of Chemistry and Biochemistry, University of Arizona, Tucson, Ariz (A.V.A.); and Trace Element Analysis Laboratory, Dartmouth College, Hanover, NH (B.P.J.)., Boice A; From the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., D.I.G., P.C.), Department of Urology (A.S.F.), and Department of Pathology (I.A.R., I.D.A.L.H., L.P.H.), Massachusetts General Hospital and Harvard Medical School, 149 13th St, Charlestown, MA 02129; Institute for Innovation in Imaging, Massachusetts General Hospital, Charlestown, Mass (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., P.C.); Harvard-MIT Health Sciences and Technology, Cambridge, Mass (D.I.G.); Bioengineering Department, Universidad Carlos III de Madrid, Madrid, Spain (D.I.G.); Department of Chemistry and Biochemistry, University of Arizona, Tucson, Ariz (A.V.A.); and Trace Element Analysis Laboratory, Dartmouth College, Hanover, NH (B.P.J.)., Rotile NJ; From the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., D.I.G., P.C.), Department of Urology (A.S.F.), and Department of Pathology (I.A.R., I.D.A.L.H., L.P.H.), Massachusetts General Hospital and Harvard Medical School, 149 13th St, Charlestown, MA 02129; Institute for Innovation in Imaging, Massachusetts General Hospital, Charlestown, Mass (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., P.C.); Harvard-MIT Health Sciences and Technology, Cambridge, Mass (D.I.G.); Bioengineering Department, Universidad Carlos III de Madrid, Madrid, Spain (D.I.G.); Department of Chemistry and Biochemistry, University of Arizona, Tucson, Ariz (A.V.A.); and Trace Element Analysis Laboratory, Dartmouth College, Hanover, NH (B.P.J.)., Ay I; From the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., D.I.G., P.C.), Department of Urology (A.S.F.), and Department of Pathology (I.A.R., I.D.A.L.H., L.P.H.), Massachusetts General Hospital and Harvard Medical School, 149 13th St, Charlestown, MA 02129; Institute for Innovation in Imaging, Massachusetts General Hospital, Charlestown, Mass (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., P.C.); Harvard-MIT Health Sciences and Technology, Cambridge, Mass (D.I.G.); Bioengineering Department, Universidad Carlos III de Madrid, Madrid, Spain (D.I.G.); Department of Chemistry and Biochemistry, University of Arizona, Tucson, Ariz (A.V.A.); and Trace Element Analysis Laboratory, Dartmouth College, Hanover, NH (B.P.J.)., Pantazopoulos P; From the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., D.I.G., P.C.), Department of Urology (A.S.F.), and Department of Pathology (I.A.R., I.D.A.L.H., L.P.H.), Massachusetts General Hospital and Harvard Medical School, 149 13th St, Charlestown, MA 02129; Institute for Innovation in Imaging, Massachusetts General Hospital, Charlestown, Mass (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., P.C.); Harvard-MIT Health Sciences and Technology, Cambridge, Mass (D.I.G.); Bioengineering Department, Universidad Carlos III de Madrid, Madrid, Spain (D.I.G.); Department of Chemistry and Biochemistry, University of Arizona, Tucson, Ariz (A.V.A.); and Trace Element Analysis Laboratory, Dartmouth College, Hanover, NH (B.P.J.)., Feldman AS; From the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., D.I.G., P.C.), Department of Urology (A.S.F.), and Department of Pathology (I.A.R., I.D.A.L.H., L.P.H.), Massachusetts General Hospital and Harvard Medical School, 149 13th St, Charlestown, MA 02129; Institute for Innovation in Imaging, Massachusetts General Hospital, Charlestown, Mass (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., P.C.); Harvard-MIT Health Sciences and Technology, Cambridge, Mass (D.I.G.); Bioengineering Department, Universidad Carlos III de Madrid, Madrid, Spain (D.I.G.); Department of Chemistry and Biochemistry, University of Arizona, Tucson, Ariz (A.V.A.); and Trace Element Analysis Laboratory, Dartmouth College, Hanover, NH (B.P.J.)., Rosales IA; From the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., D.I.G., P.C.), Department of Urology (A.S.F.), and Department of Pathology (I.A.R., I.D.A.L.H., L.P.H.), Massachusetts General Hospital and Harvard Medical School, 149 13th St, Charlestown, MA 02129; Institute for Innovation in Imaging, Massachusetts General Hospital, Charlestown, Mass (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., P.C.); Harvard-MIT Health Sciences and Technology, Cambridge, Mass (D.I.G.); Bioengineering Department, Universidad Carlos III de Madrid, Madrid, Spain (D.I.G.); Department of Chemistry and Biochemistry, University of Arizona, Tucson, Ariz (A.V.A.); and Trace Element Analysis Laboratory, Dartmouth College, Hanover, NH (B.P.J.)., How IDAL; From the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., D.I.G., P.C.), Department of Urology (A.S.F.), and Department of Pathology (I.A.R., I.D.A.L.H., L.P.H.), Massachusetts General Hospital and Harvard Medical School, 149 13th St, Charlestown, MA 02129; Institute for Innovation in Imaging, Massachusetts General Hospital, Charlestown, Mass (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., P.C.); Harvard-MIT Health Sciences and Technology, Cambridge, Mass (D.I.G.); Bioengineering Department, Universidad Carlos III de Madrid, Madrid, Spain (D.I.G.); Department of Chemistry and Biochemistry, University of Arizona, Tucson, Ariz (A.V.A.); and Trace Element Analysis Laboratory, Dartmouth College, Hanover, NH (B.P.J.)., Izquierdo-Garcia D; From the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., D.I.G., P.C.), Department of Urology (A.S.F.), and Department of Pathology (I.A.R., I.D.A.L.H., L.P.H.), Massachusetts General Hospital and Harvard Medical School, 149 13th St, Charlestown, MA 02129; Institute for Innovation in Imaging, Massachusetts General Hospital, Charlestown, Mass (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., P.C.); Harvard-MIT Health Sciences and Technology, Cambridge, Mass (D.I.G.); Bioengineering Department, Universidad Carlos III de Madrid, Madrid, Spain (D.I.G.); Department of Chemistry and Biochemistry, University of Arizona, Tucson, Ariz (A.V.A.); and Trace Element Analysis Laboratory, Dartmouth College, Hanover, NH (B.P.J.)., Hariri LP; From the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., D.I.G., P.C.), Department of Urology (A.S.F.), and Department of Pathology (I.A.R., I.D.A.L.H., L.P.H.), Massachusetts General Hospital and Harvard Medical School, 149 13th St, Charlestown, MA 02129; Institute for Innovation in Imaging, Massachusetts General Hospital, Charlestown, Mass (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., P.C.); Harvard-MIT Health Sciences and Technology, Cambridge, Mass (D.I.G.); Bioengineering Department, Universidad Carlos III de Madrid, Madrid, Spain (D.I.G.); Department of Chemistry and Biochemistry, University of Arizona, Tucson, Ariz (A.V.A.); and Trace Element Analysis Laboratory, Dartmouth College, Hanover, NH (B.P.J.)., Astashkin AV; From the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., D.I.G., P.C.), Department of Urology (A.S.F.), and Department of Pathology (I.A.R., I.D.A.L.H., L.P.H.), Massachusetts General Hospital and Harvard Medical School, 149 13th St, Charlestown, MA 02129; Institute for Innovation in Imaging, Massachusetts General Hospital, Charlestown, Mass (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., P.C.); Harvard-MIT Health Sciences and Technology, Cambridge, Mass (D.I.G.); Bioengineering Department, Universidad Carlos III de Madrid, Madrid, Spain (D.I.G.); Department of Chemistry and Biochemistry, University of Arizona, Tucson, Ariz (A.V.A.); and Trace Element Analysis Laboratory, Dartmouth College, Hanover, NH (B.P.J.)., Jackson BP; From the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., D.I.G., P.C.), Department of Urology (A.S.F.), and Department of Pathology (I.A.R., I.D.A.L.H., L.P.H.), Massachusetts General Hospital and Harvard Medical School, 149 13th St, Charlestown, MA 02129; Institute for Innovation in Imaging, Massachusetts General Hospital, Charlestown, Mass (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., P.C.); Harvard-MIT Health Sciences and Technology, Cambridge, Mass (D.I.G.); Bioengineering Department, Universidad Carlos III de Madrid, Madrid, Spain (D.I.G.); Department of Chemistry and Biochemistry, University of Arizona, Tucson, Ariz (A.V.A.); and Trace Element Analysis Laboratory, Dartmouth College, Hanover, NH (B.P.J.)., Caravan P; From the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., D.I.G., P.C.), Department of Urology (A.S.F.), and Department of Pathology (I.A.R., I.D.A.L.H., L.P.H.), Massachusetts General Hospital and Harvard Medical School, 149 13th St, Charlestown, MA 02129; Institute for Innovation in Imaging, Massachusetts General Hospital, Charlestown, Mass (M.L.F., B.F.M., I.Y.Z., S.Z., A.B., N.J.R., I.A., P.P., P.C.); Harvard-MIT Health Sciences and Technology, Cambridge, Mass (D.I.G.); Bioengineering Department, Universidad Carlos III de Madrid, Madrid, Spain (D.I.G.); Department of Chemistry and Biochemistry, University of Arizona, Tucson, Ariz (A.V.A.); and Trace Element Analysis Laboratory, Dartmouth College, Hanover, NH (B.P.J.).
Source: Radiology [Radiology] 2023 Oct; Vol. 309 (1), pp. e230984.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Radiological Society of North America Country of Publication: United States NLM ID: 0401260 Publication Model: Print Cited Medium: Internet ISSN: 1527-1315 (Electronic) Linking ISSN: 00338419 NLM ISO Abbreviation: Radiology Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1527-1315
DOI:10.1148/radiol.230984