Unraveling the Mechanism of Epichaperome Modulation by Zelavespib: Biochemical Insights on Target Occupancy and Extended Residence Time at the Site of Action.

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Title: Unraveling the Mechanism of Epichaperome Modulation by Zelavespib: Biochemical Insights on Target Occupancy and Extended Residence Time at the Site of Action.
Authors: Sharma S; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Joshi S; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Kalidindi T; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Digwal CS; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Panchal P; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Lee SG; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Zanzonico P; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Pillarsetty N; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Chiosis G; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.; Breast Cancer Medicine Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Source: Biomedicines [Biomedicines] 2023 Sep 22; Vol. 11 (10). Date of Electronic Publication: 2023 Sep 22.
Publication Type: Journal Article
Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101691304 Publication Model: Electronic Cited Medium: Print ISSN: 2227-9059 (Print) Linking ISSN: 22279059 NLM ISO Abbreviation: Biomedicines Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2227-9059
DOI:10.3390/biomedicines11102599