A dual sgRNA library design to probe genetic modifiers using genome-wide CRISPRi screens.
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| Title: | A dual sgRNA library design to probe genetic modifiers using genome-wide CRISPRi screens. |
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| Authors: | Guna A; Division of Biology and Biological Engineering, California Institute of Technology, 1200 E. California Ave, Pasadena, CA, 91125, USA.; Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA, 02142, USA., Page KR; Division of Biology and Biological Engineering, California Institute of Technology, 1200 E. California Ave, Pasadena, CA, 91125, USA., Replogle JM; Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA, 02142, USA.; Medical Scientist Training Program, University of California, San Francisco, San Francisco, CA, 94158, USA.; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, 02142, USA., Esantsi TK; Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA, 02142, USA.; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, 02142, USA., Wang ML; Division of Biology and Biological Engineering, California Institute of Technology, 1200 E. California Ave, Pasadena, CA, 91125, USA.; Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA, 02142, USA., Weissman JS; Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA, 02142, USA.; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, 02142, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02142, USA.; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, 02142, USA., Voorhees RM; Division of Biology and Biological Engineering, California Institute of Technology, 1200 E. California Ave, Pasadena, CA, 91125, USA. voorhees@caltech.edu.; Howard Hughes Medical Institute Freeman Hrabowski Scholar, California Institute of Technology, Pasadena, CA, 91125, USA. voorhees@caltech.edu. |
| Source: | BMC genomics [BMC Genomics] 2023 Oct 30; Vol. 24 (1), pp. 651. Date of Electronic Publication: 2023 Oct 30. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164 (Electronic) Linking ISSN: 14712164 NLM ISO Abbreviation: BMC Genomics Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1471-2164 |
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| DOI: | 10.1186/s12864-023-09754-y |
