Diagnostic accuracy of a three-gene Mycobacterium tuberculosis host response cartridge using fingerstick blood for childhood tuberculosis: a multicentre prospective study in low-income and middle-income countries.

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Title: Diagnostic accuracy of a three-gene Mycobacterium tuberculosis host response cartridge using fingerstick blood for childhood tuberculosis: a multicentre prospective study in low-income and middle-income countries.
Authors: Olbrich L; Division of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany; German Centre for Infection Research (DZIF), Partner Site Munich, Munich, Germany; Fraunhofer Institute ITMP, Immunology, Infection and Pandemic Research, Munich, Germany; Oxford Vaccine Group, Department of Paediatrics and the NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Verghese VP; Pediatric Infectious Diseases, Department of Pediatrics, Christian Medical College, Vellore, India., Franckling-Smith Z; Department of Paediatrics and Child Health, SA-MRC Unit on Child and Adolescent Health, University of Cape Town, Cape Town, South Africa., Sabi I; Mbeya Medical Research Centre, National Institute for Medical Research, Mbeya, Tanzania., Ntinginya NE; Mbeya Medical Research Centre, National Institute for Medical Research, Mbeya, Tanzania., Mfinanga A; Mbeya Medical Research Centre, National Institute for Medical Research, Mbeya, Tanzania., Banze D; Instituto Nacional de Saúde, Marracuene, Mozambique., Viegas S; Instituto Nacional de Saúde, Marracuene, Mozambique., Khosa C; Instituto Nacional de Saúde, Marracuene, Mozambique., Semphere R; Helse Nord Tuberculosis Initiative, Department of Pathology, Kamuzu University of Health Sciences, Blantyre, Malawi., Nliwasa M; Helse Nord Tuberculosis Initiative, Department of Pathology, Kamuzu University of Health Sciences, Blantyre, Malawi., McHugh TD; Centre for Clinical Microbiology, University College London, London, UK., Larsson L; Division of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany; German Centre for Infection Research (DZIF), Partner Site Munich, Munich, Germany., Razid A; Division of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany; German Centre for Infection Research (DZIF), Partner Site Munich, Munich, Germany., Song R; Oxford Vaccine Group, Department of Paediatrics and the NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Corbett EL; Helse Nord Tuberculosis Initiative, Department of Pathology, Kamuzu University of Health Sciences, Blantyre, Malawi; Clinical Research Department, London School of Hygiene & Tropical Medicine, London, UK., Nabeta P; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland., Trollip A; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland., Graham SM; Department of Paediatrics, University of Melbourne and Murdoch Children's Research Institute, Melbourne, VIC, Australia., Hoelscher M; Division of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany; CIHLMU Center for International Health, LMU University Hospital, LMU Munich, Munich, Germany; German Centre for Infection Research (DZIF), Partner Site Munich, Munich, Germany; Fraunhofer Institute ITMP, Immunology, Infection and Pandemic Research, Munich, Germany; Unit Global Health, Helmholtz Zentrum München, German Research Center for Environmental Health (HMGU), Neuherberg, Germany., Geldmacher C; Division of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany; German Centre for Infection Research (DZIF), Partner Site Munich, Munich, Germany; Fraunhofer Institute ITMP, Immunology, Infection and Pandemic Research, Munich, Germany., Zar HJ; Department of Paediatrics and Child Health, SA-MRC Unit on Child and Adolescent Health, University of Cape Town, Cape Town, South Africa., Michael JS; Department of Clinical Microbiology, Christian Medical College, Vellore, India., Heinrich N; Division of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany; CIHLMU Center for International Health, LMU University Hospital, LMU Munich, Munich, Germany; German Centre for Infection Research (DZIF), Partner Site Munich, Munich, Germany; Fraunhofer Institute ITMP, Immunology, Infection and Pandemic Research, Munich, Germany. Electronic address: norbert.heinrich@med.uni-muenchen.de.
Corporate Authors: RaPaed-TB consortium
Source: The Lancet. Infectious diseases [Lancet Infect Dis] 2024 Feb; Vol. 24 (2), pp. 140-149. Date of Electronic Publication: 2023 Oct 30.
Publication Type: Multicenter Study; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 101130150 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-4457 (Electronic) Linking ISSN: 14733099 NLM ISO Abbreviation: Lancet Infect Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1474-4457
DOI:10.1016/S1473-3099(23)00491-7