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Diagnostic accuracy of a three-gene Mycobacterium tuberculosis host response cartridge using fingerstick blood for childhood tuberculosis: a multicentre prospective study in low-income and middle-income countries.

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Title: Diagnostic accuracy of a three-gene Mycobacterium tuberculosis host response cartridge using fingerstick blood for childhood tuberculosis: a multicentre prospective study in low-income and middle-income countries.
Authors: Olbrich L; Division of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany; German Centre for Infection Research (DZIF), Partner Site Munich, Munich, Germany; Fraunhofer Institute ITMP, Immunology, Infection and Pandemic Research, Munich, Germany; Oxford Vaccine Group, Department of Paediatrics and the NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Verghese VP; Pediatric Infectious Diseases, Department of Pediatrics, Christian Medical College, Vellore, India., Franckling-Smith Z; Department of Paediatrics and Child Health, SA-MRC Unit on Child and Adolescent Health, University of Cape Town, Cape Town, South Africa., Sabi I; Mbeya Medical Research Centre, National Institute for Medical Research, Mbeya, Tanzania., Ntinginya NE; Mbeya Medical Research Centre, National Institute for Medical Research, Mbeya, Tanzania., Mfinanga A; Mbeya Medical Research Centre, National Institute for Medical Research, Mbeya, Tanzania., Banze D; Instituto Nacional de Saúde, Marracuene, Mozambique., Viegas S; Instituto Nacional de Saúde, Marracuene, Mozambique., Khosa C; Instituto Nacional de Saúde, Marracuene, Mozambique., Semphere R; Helse Nord Tuberculosis Initiative, Department of Pathology, Kamuzu University of Health Sciences, Blantyre, Malawi., Nliwasa M; Helse Nord Tuberculosis Initiative, Department of Pathology, Kamuzu University of Health Sciences, Blantyre, Malawi., McHugh TD; Centre for Clinical Microbiology, University College London, London, UK., Larsson L; Division of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany; German Centre for Infection Research (DZIF), Partner Site Munich, Munich, Germany., Razid A; Division of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany; German Centre for Infection Research (DZIF), Partner Site Munich, Munich, Germany., Song R; Oxford Vaccine Group, Department of Paediatrics and the NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Corbett EL; Helse Nord Tuberculosis Initiative, Department of Pathology, Kamuzu University of Health Sciences, Blantyre, Malawi; Clinical Research Department, London School of Hygiene & Tropical Medicine, London, UK., Nabeta P; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland., Trollip A; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland., Graham SM; Department of Paediatrics, University of Melbourne and Murdoch Children's Research Institute, Melbourne, VIC, Australia., Hoelscher M; Division of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany; CIHLMU Center for International Health, LMU University Hospital, LMU Munich, Munich, Germany; German Centre for Infection Research (DZIF), Partner Site Munich, Munich, Germany; Fraunhofer Institute ITMP, Immunology, Infection and Pandemic Research, Munich, Germany; Unit Global Health, Helmholtz Zentrum München, German Research Center for Environmental Health (HMGU), Neuherberg, Germany., Geldmacher C; Division of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany; German Centre for Infection Research (DZIF), Partner Site Munich, Munich, Germany; Fraunhofer Institute ITMP, Immunology, Infection and Pandemic Research, Munich, Germany., Zar HJ; Department of Paediatrics and Child Health, SA-MRC Unit on Child and Adolescent Health, University of Cape Town, Cape Town, South Africa., Michael JS; Department of Clinical Microbiology, Christian Medical College, Vellore, India., Heinrich N; Division of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany; CIHLMU Center for International Health, LMU University Hospital, LMU Munich, Munich, Germany; German Centre for Infection Research (DZIF), Partner Site Munich, Munich, Germany; Fraunhofer Institute ITMP, Immunology, Infection and Pandemic Research, Munich, Germany. Electronic address: norbert.heinrich@med.uni-muenchen.de.
Corporate Authors: RaPaed-TB consortium
Source: The Lancet. Infectious diseases [Lancet Infect Dis] 2024 Feb; Vol. 24 (2), pp. 140-149. Date of Electronic Publication: 2023 Oct 30.
Publication Type: Multicenter Study; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 101130150 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-4457 (Electronic) Linking ISSN: 14733099 NLM ISO Abbreviation: Lancet Infect Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Diagnostic accuracy of a three-gene Mycobacterium tuberculosis host response cartridge using fingerstick blood for childhood tuberculosis: a multicentre prospective study in low-income and middle-income countries.
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  Data: <searchLink fieldCode="AU" term="%22Olbrich+L%22">Olbrich L</searchLink>; Division of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany; German Centre for Infection Research (DZIF), Partner Site Munich, Munich, Germany; Fraunhofer Institute ITMP, Immunology, Infection and Pandemic Research, Munich, Germany; Oxford Vaccine Group, Department of Paediatrics and the NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Verghese+VP%22">Verghese VP</searchLink>; Pediatric Infectious Diseases, Department of Pediatrics, Christian Medical College, Vellore, India.<br /><searchLink fieldCode="AU" term="%22Franckling-Smith+Z%22">Franckling-Smith Z</searchLink>; Department of Paediatrics and Child Health, SA-MRC Unit on Child and Adolescent Health, University of Cape Town, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Sabi+I%22">Sabi I</searchLink>; Mbeya Medical Research Centre, National Institute for Medical Research, Mbeya, Tanzania.<br /><searchLink fieldCode="AU" term="%22Ntinginya+NE%22">Ntinginya NE</searchLink>; Mbeya Medical Research Centre, National Institute for Medical Research, Mbeya, Tanzania.<br /><searchLink fieldCode="AU" term="%22Mfinanga+A%22">Mfinanga A</searchLink>; Mbeya Medical Research Centre, National Institute for Medical Research, Mbeya, Tanzania.<br /><searchLink fieldCode="AU" term="%22Banze+D%22">Banze D</searchLink>; Instituto Nacional de Saúde, Marracuene, Mozambique.<br /><searchLink fieldCode="AU" term="%22Viegas+S%22">Viegas S</searchLink>; Instituto Nacional de Saúde, Marracuene, Mozambique.<br /><searchLink fieldCode="AU" term="%22Khosa+C%22">Khosa C</searchLink>; Instituto Nacional de Saúde, Marracuene, Mozambique.<br /><searchLink fieldCode="AU" term="%22Semphere+R%22">Semphere R</searchLink>; Helse Nord Tuberculosis Initiative, Department of Pathology, Kamuzu University of Health Sciences, Blantyre, Malawi.<br /><searchLink fieldCode="AU" term="%22Nliwasa+M%22">Nliwasa M</searchLink>; Helse Nord Tuberculosis Initiative, Department of Pathology, Kamuzu University of Health Sciences, Blantyre, Malawi.<br /><searchLink fieldCode="AU" term="%22McHugh+TD%22">McHugh TD</searchLink>; Centre for Clinical Microbiology, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Larsson+L%22">Larsson L</searchLink>; Division of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany; German Centre for Infection Research (DZIF), Partner Site Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Razid+A%22">Razid A</searchLink>; Division of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany; German Centre for Infection Research (DZIF), Partner Site Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Song+R%22">Song R</searchLink>; Oxford Vaccine Group, Department of Paediatrics and the NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Corbett+EL%22">Corbett EL</searchLink>; Helse Nord Tuberculosis Initiative, Department of Pathology, Kamuzu University of Health Sciences, Blantyre, Malawi; Clinical Research Department, London School of Hygiene & Tropical Medicine, London, UK.<br /><searchLink fieldCode="AU" term="%22Nabeta+P%22">Nabeta P</searchLink>; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Trollip+A%22">Trollip A</searchLink>; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Graham+SM%22">Graham SM</searchLink>; Department of Paediatrics, University of Melbourne and Murdoch Children's Research Institute, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Hoelscher+M%22">Hoelscher M</searchLink>; Division of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany; CIHLMU Center for International Health, LMU University Hospital, LMU Munich, Munich, Germany; German Centre for Infection Research (DZIF), Partner Site Munich, Munich, Germany; Fraunhofer Institute ITMP, Immunology, Infection and Pandemic Research, Munich, Germany; Unit Global Health, Helmholtz Zentrum München, German Research Center for Environmental Health (HMGU), Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Geldmacher+C%22">Geldmacher C</searchLink>; Division of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany; German Centre for Infection Research (DZIF), Partner Site Munich, Munich, Germany; Fraunhofer Institute ITMP, Immunology, Infection and Pandemic Research, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Zar+HJ%22">Zar HJ</searchLink>; Department of Paediatrics and Child Health, SA-MRC Unit on Child and Adolescent Health, University of Cape Town, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Michael+JS%22">Michael JS</searchLink>; Department of Clinical Microbiology, Christian Medical College, Vellore, India.<br /><searchLink fieldCode="AU" term="%22Heinrich+N%22">Heinrich N</searchLink>; Division of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany; CIHLMU Center for International Health, LMU University Hospital, LMU Munich, Munich, Germany; German Centre for Infection Research (DZIF), Partner Site Munich, Munich, Germany; Fraunhofer Institute ITMP, Immunology, Infection and Pandemic Research, Munich, Germany. Electronic address: norbert.heinrich@med.uni-muenchen.de.
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  Data: <searchLink fieldCode="JN" term="%22101130150%22">The Lancet. Infectious diseases</searchLink> [Lancet Infect Dis] 2024 Feb; Vol. 24 (2), pp. 140-149. <i>Date of Electronic Publication: </i>2023 Oct 30.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101130150 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1474-4457 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214733099%22">14733099 </searchLink><i>NLM ISO Abbreviation: </i>Lancet Infect Dis <i>Subsets: </i>MEDLINE
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