Fixed-duration ibrutinib-venetoclax versus chlorambucil-obinutuzumab in previously untreated chronic lymphocytic leukaemia (GLOW): 4-year follow-up from a multicentre, open-label, randomised, phase 3 trial.

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Title: Fixed-duration ibrutinib-venetoclax versus chlorambucil-obinutuzumab in previously untreated chronic lymphocytic leukaemia (GLOW): 4-year follow-up from a multicentre, open-label, randomised, phase 3 trial.
Authors: Niemann CU; Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark. Electronic address: carsten.utoft.niemann@regionh.dk., Munir T; St James's Hospital, Leeds, UK., Moreno C; Hospital de la Santa Creu i Sant Pau, Autonomous University of Barcelona, Josep Carreras Leukaemia Research Institute, Barcelona, Spain., Owen C; Tom Baker Cancer Centre, Calgary, AB, Canada., Follows GA; Addenbrookes Hospital, Cambridge, UK., Benjamini O; Sheba Medical Center, Ramat Gan, Israel., Janssens A; UZ Leuven Gasthuisberg, Leuven, Belgium., Levin MD; Albert Schweitzer Hospital, Dordrecht, Netherlands., Robak T; Medical University of Lodz, Copernicus Memorial Hospital, Lodz, Poland., Simkovic M; 4th Department of Internal Medicine-Haematology, Faculty of Medicine in Hradec Králové, University Hospital and Charles University in Prague, Hradec Králové, Czech Republic., Voloshin S; Russian Scientific and Research Institute of Hematology and Transfusiology, St Petersburg, Russia., Vorobyev V; SP Botkin Moscow City Clinical Hospital, Moscow, Russia., Yagci M; Gazi Universitesi Tip Fakultesi, Ankara, Türkiye., Ysebaert L; Institut Universitaire du Cancer Toulouse Oncopole, Toulouse, France., Qi K; Janssen Research & Development, Titusville, NJ, USA., Qi Q; Janssen Research & Development, Raritan, NJ, USA., Sinet P; Janssen Research & Development, Bridgewater, NJ, USA., Parisi L; Janssen Research & Development, Raritan, NJ, USA., Srinivasan S; Oncology Translational Research, Janssen Research & Development, Lower Gwynedd Township, PA, USA., Schuier N; Janssen Research & Development, Raritan, NJ, USA., Baeten K; Janssen Research & Development, Beerse, Belgium., Howes A; Janssen Research & Development, High Wycombe, UK., Caces DB; Janssen Research & Development, Raritan, NJ, USA., Kater AP; Amsterdam University Medical Centers, Cancer Center Amsterdam, University of Amsterdam, Amsterdam, Netherlands.
Source: The Lancet. Oncology [Lancet Oncol] 2023 Dec; Vol. 24 (12), pp. 1423-1433. Date of Electronic Publication: 2023 Nov 06.
Publication Type: Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase III; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Lancet Pub. Group Country of Publication: England NLM ID: 100957246 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-5488 (Electronic) Linking ISSN: 14702045 NLM ISO Abbreviation: Lancet Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1474-5488
DOI:10.1016/S1470-2045(23)00452-7