Multiplexed detection of viral antigen and RNA using nanopore sensing and encoded molecular probes.
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| Title: | Multiplexed detection of viral antigen and RNA using nanopore sensing and encoded molecular probes. |
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| Authors: | Ren R; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, 82 Wood Lane, London, W12 0BZ, UK.; Department of Metabolism, Digestion and Reproduction, Imperial College London, Hammersmith Campus, Du Cane Road, London, W12 0NN, UK., Cai S; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, 82 Wood Lane, London, W12 0BZ, UK. shenglin.cai15@imperial.ac.uk.; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK. shenglin.cai15@imperial.ac.uk., Fang X; The Key Laboratory of Zhejiang Province for Aptamers and Theranostics, Aptamer Selection Center, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, 310022, Hangzhou, Zhejiang, China., Wang X; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, 82 Wood Lane, London, W12 0BZ, UK., Zhang Z; The Key Laboratory of Zhejiang Province for Aptamers and Theranostics, Aptamer Selection Center, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, 310022, Hangzhou, Zhejiang, China., Damiani M; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, 82 Wood Lane, London, W12 0BZ, UK., Hudlerova C; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, 82 Wood Lane, London, W12 0BZ, UK., Rosa A; The Chromatin Structure and Mobile DNA Laboratory, The Francis Crick Institute, London, UK.; Wolfson Education Centre, Faculty of Medicine, Imperial College London, London, UK., Hope J; The Chromatin Structure and Mobile DNA Laboratory, The Francis Crick Institute, London, UK., Cook NJ; The Chromatin Structure and Mobile DNA Laboratory, The Francis Crick Institute, London, UK., Gorelkin P; National University of Science and Technology 'MISIS', Leninskiy Prospect 4, 119991, Moscow, Russian Federation., Erofeev A; National University of Science and Technology 'MISIS', Leninskiy Prospect 4, 119991, Moscow, Russian Federation., Novak P; ICAPPIC Limited, The Fisheries, Mentmore Terrace, London, E8 3PN, UK., Badhan A; Molecular Diagnostic Unit, Section of Virology, Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, UK., Crone M; Section of Structural and Synthetic Biology, Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, UK., Freemont P; Section of Structural and Synthetic Biology, Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, UK., Taylor GP; Molecular Diagnostic Unit, Section of Virology, Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, UK., Tang L; State Key Laboratory of Modern Optical Instrumentation, College of Optical Science and Engineering, International Research Center for Advanced Photonics, Zhejiang University, 310027, Hangzhou, China., Edwards C; Department of Metabolism, Digestion and Reproduction, Imperial College London, Hammersmith Campus, Du Cane Road, London, W12 0NN, UK.; ICAPPIC Limited, The Fisheries, Mentmore Terrace, London, E8 3PN, UK., Shevchuk A; Department of Metabolism, Digestion and Reproduction, Imperial College London, Hammersmith Campus, Du Cane Road, London, W12 0NN, UK., Cherepanov P; The Chromatin Structure and Mobile DNA Laboratory, The Francis Crick Institute, London, UK.; Molecular Diagnostic Unit, Section of Virology, Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, UK., Luo Z; The Key Laboratory of Zhejiang Province for Aptamers and Theranostics, Aptamer Selection Center, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, 310022, Hangzhou, Zhejiang, China., Tan W; The Key Laboratory of Zhejiang Province for Aptamers and Theranostics, Aptamer Selection Center, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, 310022, Hangzhou, Zhejiang, China. tan@hnu.edu.cn., Korchev Y; Department of Metabolism, Digestion and Reproduction, Imperial College London, Hammersmith Campus, Du Cane Road, London, W12 0NN, UK.; Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, Kakuma-machi, Kanazawa, 920-1192, Japan., Ivanov AP; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, 82 Wood Lane, London, W12 0BZ, UK. alex.ivanov@imperial.ac.uk., Edel JB; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, 82 Wood Lane, London, W12 0BZ, UK. joshua.edel@imperial.ac.uk. |
| Source: | Nature communications [Nat Commun] 2023 Nov 14; Vol. 14 (1), pp. 7362. Date of Electronic Publication: 2023 Nov 14. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-023-43004-9 |
