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Antitumor activity of AZD0754, a dnTGFβRII-armored, STEAP2-targeted CAR-T cell therapy, in prostate cancer.

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Bibliographic Details
Title: Antitumor activity of AZD0754, a dnTGFβRII-armored, STEAP2-targeted CAR-T cell therapy, in prostate cancer.
Authors: Zanvit P; Early Oncology Research., van Dyk D; Biologics Engineering., Fazenbaker C; Early Oncology Research., McGlinchey K; Early Oncology Research., Luo W; Early Oncology Research., Pezold JM; Early Oncology Research., Meekin J; Early Oncology Research., Chang CY; Biologics Engineering., Carrasco RA; Early Oncology Research., Breen S; Early Oncology Research., Cheung CS; Biologics Engineering., Endlich-Frazier A; Biologics Engineering., Clark B; Biologics Engineering., Chu NJ; Early Oncology Research., Vantellini A; Discovery Sciences, Oncology R&D, and., Martin PL; Oncology Translational Medicine, Oncology R&D, AstraZeneca, Gaithersburg, Maryland, USA., Hoover CE; Clinical Pathology Patient Safety, BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom., Riley K; Clinical Pathology Patient Safety, BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom., Sweet SM; Oncology Translational Medicine, Oncology R&D, AstraZeneca, Gaithersburg, Maryland, USA., Chain D; Oncology Translational Medicine, Oncology R&D, AstraZeneca, Gaithersburg, Maryland, USA., Kim YJ; Oncology Translational Medicine, Oncology R&D, AstraZeneca, Gaithersburg, Maryland, USA., Tu E; Oncology Translational Medicine, Oncology R&D, AstraZeneca, Gaithersburg, Maryland, USA., Harder N; Computational Pathology, AstraZeneca, Munich, Germany., Phipps S; Biologics Engineering., Damschroder M; Biologics Engineering., Gilbreth RN; Biologics Engineering., Cobbold M; Early Oncology Research., Moody G; Early Oncology Research., Bosco EE; Early Oncology Research.
Source: The Journal of clinical investigation [J Clin Invest] 2023 Nov 15; Vol. 133 (22). Date of Electronic Publication: 2023 Nov 15.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1558-8238
DOI:10.1172/JCI169655