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Concurrent RB1 loss and BRCA-deficiency predicts enhanced immunological response and long-term survival in tubo-ovarian high-grade serous carcinoma.

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Title: Concurrent RB1 loss and BRCA-deficiency predicts enhanced immunological response and long-term survival in tubo-ovarian high-grade serous carcinoma.
Authors: Saner FAM; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Department of Obstetrics and Gynecology, Bern University Hospital and University of Bern, Bern, Switzerland., Takahashi K; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Department of Obstetrics and Gynecology, The Jikei University School of Medicine, Tokyo, Japan., Budden T; School of Clinical Medicine, UNSW Medicine and Health, University of NSW Sydney, Sydney, New South Wales, Australia.; Skin Cancer and Ageing Lab, Cancer Research United Kingdom Manchester Institute, The University of Manchester, Manchester, UK., Pandey A; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Ariyaratne D; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Zwimpfer TA; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Meagher NS; School of Clinical Medicine, UNSW Medicine and Health, University of NSW Sydney, Sydney, New South Wales, Australia.; The Daffodil Centre, The University of Sydney, a joint venture with Cancer Council NSW, Sydney, New South Wales, Australia., Fereday S; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Twomey L; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Pishas KI; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Hoang T; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Bolithon A; School of Clinical Medicine, UNSW Medicine and Health, University of NSW Sydney, Sydney, New South Wales, Australia.; Adult Cancer Program, Lowy Cancer Research Centre, University of NSW Sydney, Sydney, New South Wales, Australia., Traficante N; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Alsop K; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Christie EL; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Kang EY; Department of Pathology and Laboratory Medicine, University of Calgary, Foothills Medical Center, Calgary, AB, Canada., Nelson GS; Department of Oncology, Division of Gynecologic Oncology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada., Ghatage P; Department of Oncology, Division of Gynecologic Oncology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada., Lee CH; Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, Canada., Riggan MJ; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Duke University Medical Center, Durham, NC, USA., Alsop J; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Beckmann MW; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany., Boros J; Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney, New South Wales, Australia.; Department of Gynaecological Oncology, Westmead Hospital, Sydney, New South Wales, Australia.; The University of Sydney, Sydney, New South Wales, Australia., Brand AH; Department of Gynaecological Oncology, Westmead Hospital, Sydney, New South Wales, Australia.; The University of Sydney, Sydney, New South Wales, Australia., Brooks-Wilson A; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada., Carney ME; Department of Obstetrics and Gynecology, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI, USA., Coulson P; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK., Courtney-Brooks M; Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Cushing-Haugen KL; Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA., Cybulski C; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland., El-Bahrawy MA; Department of Metabolism, Digestion and Reproduction, Imperial College London, Hammersmith Hospital, London, UK., Elishaev E; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Erber R; Institute of Pathology, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany., Gayther SA; Center for Bioinformatics and Functional Genomics and the Cedars Sinai Genomics Core, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Gentry-Maharaj A; MRC Clinical Trials Unit, Institute of Clinical Trials and Methodology, University College London, London, UK.; Department of Women's Cancer, Elizabeth Garrett Anderson Institute for Women's Health, University College London, London, UK., Blake Gilks C; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada., Harnett PR; The University of Sydney, Sydney, New South Wales, Australia.; Crown Princess Mary Cancer Centre, Westmead Hospital, Sydney, New South Wales, Australia., Harris HR; Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA., Hartmann A; Institute of Pathology, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany., Hein A; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany., Hendley J; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Hernandez BY; University of Hawaii Cancer Center, Honolulu, HI, USA., Jakubowska A; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland.; Independent Laboratory of Molecular Biology and Genetic Diagnostics, Pomeranian Medical University, Szczecin, Poland., Jimenez-Linan M; Department of Histopathology, Addenbrooke's Hospital, Cambridge, UK., Jones ME; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK., Kaufmann SH; Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN, USA., Kennedy CJ; Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney, New South Wales, Australia.; The University of Sydney, Sydney, New South Wales, Australia., Kluz T; Department of Gynecology and Obstetrics, Gynecology Oncology and Obstetrics, Institute of Medical Sciences, Medical College of Rzeszow University, Rzeszów, Poland., Koziak JM; Alberta Health Services-Cancer Care, Calgary, AB, Canada., Kristjansdottir B; Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Center for Cancer Research, University of Gothenburg, Gothenburg, Sweden., Le ND; Cancer Control Research, BC Cancer Agency, Vancouver, BC, Canada., Lener M; International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University in Szczecin, Szczecin, Poland., Lester J; David Geffen School of Medicine, Department of Obstetrics and Gynecology, University of California at Los Angeles, Los Angeles, CA, USA., Lubiński J; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland., Mateoiu C; Department of Pathology, University of Gothenburg, Gothenburg, Sweden., Orsulic S; David Geffen School of Medicine, Department of Obstetrics and Gynecology, University of California at Los Angeles, Los Angeles, CA, USA., Ruebner M; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany., Schoemaker MJ; Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Shah M; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Sharma R; Tissue Pathology and Diagnostic Oncology, Westmead Hospital, Sydney, New South Wales, Australia., Sherman ME; Department of Health Sciences Research, Mayo Clinic, Jacksonville, FL, USA., Shvetsov YB; University of Hawaii Cancer Center, Honolulu, HI, USA., Singh N; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada., Rinda Soong T; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Steed H; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Alberta, Edmonton, Alberta, Canada.; Section of Gynecologic Oncology Surgery, North Zone, Alberta Health Services, Edmonton, Alberta, Canada., Sukumvanich P; Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Talhouk A; British Columbia's Gynecological Cancer Research Team (OVCARE), University of British Columbia, BC Cancer, and Vancouver General Hospital, Vancouver, BC, Canada.; Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, BC, Canada., Taylor SE; Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Vierkant RA; Department of Quantitative Health Sciences, Division of Clinical Trials and Biostatistics, Mayo Clinic, Rochester, MN, USA., Wang C; Department of Quantitative Health Sciences, Division of Computational Biology, Mayo Clinic, Rochester, MN, USA., Widschwendter M; EUTOPS Institute, University of Innsbruck, Innsbruck, Austria., Wilkens LR; University of Hawaii Cancer Center, Honolulu, HI, USA., Winham SJ; Department of Quantitative Health Sciences, Division of Computational Biology, Mayo Clinic, Rochester, MN, USA., Anglesio MS; British Columbia's Gynecological Cancer Research Team (OVCARE), University of British Columbia, BC Cancer, and Vancouver General Hospital, Vancouver, BC, Canada.; Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, BC, Canada., Berchuck A; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Duke University Medical Center, Durham, NC, USA., Brenton JD; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK., Campbell I; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Cook LS; Epidemiology, School of Public Health, University of Colorado, Aurora, CO, USA.; Community Health Sciences, University of Calgary, Calgary, AB, Canada., Doherty JA; Huntsman Cancer Institute, Department of Population Health Sciences, University of Utah, Salt Lake City, UT, USA., Fasching PA; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany., Fortner RT; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Research, Cancer Registry of Norway, Oslo, Norway., Goodman MT; Cancer Prevention and Control Program, Cedars-Sinai Cancer, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Gronwald J; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland., Huntsman DG; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.; British Columbia's Gynecological Cancer Research Team (OVCARE), University of British Columbia, BC Cancer, and Vancouver General Hospital, Vancouver, BC, Canada.; Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, BC, Canada.; Department of Molecular Oncology, BC Cancer Research Centre, Vancouver, BC, Canada., Karlan BY; David Geffen School of Medicine, Department of Obstetrics and Gynecology, University of California at Los Angeles, Los Angeles, CA, USA., Kelemen LE; Division of Acute Disease Epidemiology, South Carolina Department of Health & Environmental Control, Columbia, SC, USA., Menon U; MRC Clinical Trials Unit, Institute of Clinical Trials and Methodology, University College London, London, UK., Modugno F; Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Department of Epidemiology, University of Pittsburgh School of Public Health, Pittsburgh, PA, USA.; Women's Cancer Research Center, Magee-Womens Research Institute and Hillman Cancer Center, Pittsburgh, PA, USA., Pharoah PDP; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.; Department of Computational Biomedicine, Cedars-Sinai Medical Center, West Hollywood, CA, USA.; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Schildkraut JM; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Sundfeldt K; Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Center for Cancer Research, University of Gothenburg, Gothenburg, Sweden., Swerdlow AJ; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.; Division of Breast Cancer Research, The Institute of Cancer Research, London, UK., Goode EL; Department of Quantitative Health Sciences, Division of Epidemiology, Mayo Clinic, Rochester, MN, USA., DeFazio A; The Daffodil Centre, The University of Sydney, a joint venture with Cancer Council NSW, Sydney, New South Wales, Australia.; Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney, New South Wales, Australia.; Department of Gynaecological Oncology, Westmead Hospital, Sydney, New South Wales, Australia.; The University of Sydney, Sydney, New South Wales, Australia., Köbel M; Department of Pathology and Laboratory Medicine, University of Calgary, Foothills Medical Center, Calgary, AB, Canada., Ramus SJ; School of Clinical Medicine, UNSW Medicine and Health, University of NSW Sydney, Sydney, New South Wales, Australia.; Adult Cancer Program, Lowy Cancer Research Centre, University of NSW Sydney, Sydney, New South Wales, Australia., Bowtell DDL; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Garsed DW; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.
Corporate Authors: AOCS Group
Source: MedRxiv : the preprint server for health sciences [medRxiv] 2023 Nov 10. Date of Electronic Publication: 2023 Nov 10.
Publication Type: Preprint; Journal Article
Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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DbLabel: MEDLINE Ultimate
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AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Concurrent RB1 loss and BRCA-deficiency predicts enhanced immunological response and long-term survival in tubo-ovarian high-grade serous carcinoma.
– Name: Author
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  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Saner+FAM%22">Saner FAM</searchLink>; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Department of Obstetrics and Gynecology, Bern University Hospital and University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Takahashi+K%22">Takahashi K</searchLink>; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Department of Obstetrics and Gynecology, The Jikei University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Budden+T%22">Budden T</searchLink>; School of Clinical Medicine, UNSW Medicine and Health, University of NSW Sydney, Sydney, New South Wales, Australia.; Skin Cancer and Ageing Lab, Cancer Research United Kingdom Manchester Institute, The University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Pandey+A%22">Pandey A</searchLink>; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Ariyaratne+D%22">Ariyaratne D</searchLink>; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Zwimpfer+TA%22">Zwimpfer TA</searchLink>; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Meagher+NS%22">Meagher NS</searchLink>; School of Clinical Medicine, UNSW Medicine and Health, University of NSW Sydney, Sydney, New South Wales, Australia.; The Daffodil Centre, The University of Sydney, a joint venture with Cancer Council NSW, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Fereday+S%22">Fereday S</searchLink>; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Twomey+L%22">Twomey L</searchLink>; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Pishas+KI%22">Pishas KI</searchLink>; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Hoang+T%22">Hoang T</searchLink>; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Bolithon+A%22">Bolithon A</searchLink>; School of Clinical Medicine, UNSW Medicine and Health, University of NSW Sydney, Sydney, New South Wales, Australia.; Adult Cancer Program, Lowy Cancer Research Centre, University of NSW Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Traficante+N%22">Traficante N</searchLink>; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Alsop+K%22">Alsop K</searchLink>; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Christie+EL%22">Christie EL</searchLink>; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Kang+EY%22">Kang EY</searchLink>; Department of Pathology and Laboratory Medicine, University of Calgary, Foothills Medical Center, Calgary, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Nelson+GS%22">Nelson GS</searchLink>; Department of Oncology, Division of Gynecologic Oncology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Ghatage+P%22">Ghatage P</searchLink>; Department of Oncology, Division of Gynecologic Oncology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Lee+CH%22">Lee CH</searchLink>; Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Riggan+MJ%22">Riggan MJ</searchLink>; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Duke University Medical Center, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Alsop+J%22">Alsop J</searchLink>; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Beckmann+MW%22">Beckmann MW</searchLink>; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Boros+J%22">Boros J</searchLink>; Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney, New South Wales, Australia.; Department of Gynaecological Oncology, Westmead Hospital, Sydney, New South Wales, Australia.; The University of Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Brand+AH%22">Brand AH</searchLink>; Department of Gynaecological Oncology, Westmead Hospital, Sydney, New South Wales, Australia.; The University of Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Brooks-Wilson+A%22">Brooks-Wilson A</searchLink>; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Carney+ME%22">Carney ME</searchLink>; Department of Obstetrics and Gynecology, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI, USA.<br /><searchLink fieldCode="AU" term="%22Coulson+P%22">Coulson P</searchLink>; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Courtney-Brooks+M%22">Courtney-Brooks M</searchLink>; Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Cushing-Haugen+KL%22">Cushing-Haugen KL</searchLink>; Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Cybulski+C%22">Cybulski C</searchLink>; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland.<br /><searchLink fieldCode="AU" term="%22El-Bahrawy+MA%22">El-Bahrawy MA</searchLink>; Department of Metabolism, Digestion and Reproduction, Imperial College London, Hammersmith Hospital, London, UK.<br /><searchLink fieldCode="AU" term="%22Elishaev+E%22">Elishaev E</searchLink>; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Erber+R%22">Erber R</searchLink>; Institute of Pathology, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Gayther+SA%22">Gayther SA</searchLink>; Center for Bioinformatics and Functional Genomics and the Cedars Sinai Genomics Core, Cedars-Sinai Medical Center, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Gentry-Maharaj+A%22">Gentry-Maharaj A</searchLink>; MRC Clinical Trials Unit, Institute of Clinical Trials and Methodology, University College London, London, UK.; Department of Women's Cancer, Elizabeth Garrett Anderson Institute for Women's Health, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Blake+Gilks+C%22">Blake Gilks C</searchLink>; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Harnett+PR%22">Harnett PR</searchLink>; The University of Sydney, Sydney, New South Wales, Australia.; Crown Princess Mary Cancer Centre, Westmead Hospital, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Harris+HR%22">Harris HR</searchLink>; Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Hartmann+A%22">Hartmann A</searchLink>; Institute of Pathology, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Hein+A%22">Hein A</searchLink>; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Hendley+J%22">Hendley J</searchLink>; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Hernandez+BY%22">Hernandez BY</searchLink>; University of Hawaii Cancer Center, Honolulu, HI, USA.<br /><searchLink fieldCode="AU" term="%22Jakubowska+A%22">Jakubowska A</searchLink>; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland.; Independent Laboratory of Molecular Biology and Genetic Diagnostics, Pomeranian Medical University, Szczecin, Poland.<br /><searchLink fieldCode="AU" term="%22Jimenez-Linan+M%22">Jimenez-Linan M</searchLink>; Department of Histopathology, Addenbrooke's Hospital, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Jones+ME%22">Jones ME</searchLink>; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Kaufmann+SH%22">Kaufmann SH</searchLink>; Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Kennedy+CJ%22">Kennedy CJ</searchLink>; Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney, New South Wales, Australia.; The University of Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Kluz+T%22">Kluz T</searchLink>; Department of Gynecology and Obstetrics, Gynecology Oncology and Obstetrics, Institute of Medical Sciences, Medical College of Rzeszow University, Rzeszów, Poland.<br /><searchLink fieldCode="AU" term="%22Koziak+JM%22">Koziak JM</searchLink>; Alberta Health Services-Cancer Care, Calgary, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Kristjansdottir+B%22">Kristjansdottir B</searchLink>; Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Center for Cancer Research, University of Gothenburg, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Le+ND%22">Le ND</searchLink>; Cancer Control Research, BC Cancer Agency, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Lener+M%22">Lener M</searchLink>; International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University in Szczecin, Szczecin, Poland.<br /><searchLink fieldCode="AU" term="%22Lester+J%22">Lester J</searchLink>; David Geffen School of Medicine, Department of Obstetrics and Gynecology, University of California at Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lubiński+J%22">Lubiński J</searchLink>; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland.<br /><searchLink fieldCode="AU" term="%22Mateoiu+C%22">Mateoiu C</searchLink>; Department of Pathology, University of Gothenburg, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Orsulic+S%22">Orsulic S</searchLink>; David Geffen School of Medicine, Department of Obstetrics and Gynecology, University of California at Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ruebner+M%22">Ruebner M</searchLink>; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Schoemaker+MJ%22">Schoemaker MJ</searchLink>; Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Shah+M%22">Shah M</searchLink>; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Sharma+R%22">Sharma R</searchLink>; Tissue Pathology and Diagnostic Oncology, Westmead Hospital, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Sherman+ME%22">Sherman ME</searchLink>; Department of Health Sciences Research, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Shvetsov+YB%22">Shvetsov YB</searchLink>; University of Hawaii Cancer Center, Honolulu, HI, USA.<br /><searchLink fieldCode="AU" term="%22Singh+N%22">Singh N</searchLink>; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Rinda+Soong+T%22">Rinda Soong T</searchLink>; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Steed+H%22">Steed H</searchLink>; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Alberta, Edmonton, Alberta, Canada.; Section of Gynecologic Oncology Surgery, North Zone, Alberta Health Services, Edmonton, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Sukumvanich+P%22">Sukumvanich P</searchLink>; Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Talhouk+A%22">Talhouk A</searchLink>; British Columbia's Gynecological Cancer Research Team (OVCARE), University of British Columbia, BC Cancer, and Vancouver General Hospital, Vancouver, BC, Canada.; Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Taylor+SE%22">Taylor SE</searchLink>; Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Vierkant+RA%22">Vierkant RA</searchLink>; Department of Quantitative Health Sciences, Division of Clinical Trials and Biostatistics, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Wang+C%22">Wang C</searchLink>; Department of Quantitative Health Sciences, Division of Computational Biology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Widschwendter+M%22">Widschwendter M</searchLink>; EUTOPS Institute, University of Innsbruck, Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Wilkens+LR%22">Wilkens LR</searchLink>; University of Hawaii Cancer Center, Honolulu, HI, USA.<br /><searchLink fieldCode="AU" term="%22Winham+SJ%22">Winham SJ</searchLink>; Department of Quantitative Health Sciences, Division of Computational Biology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Anglesio+MS%22">Anglesio MS</searchLink>; British Columbia's Gynecological Cancer Research Team (OVCARE), University of British Columbia, BC Cancer, and Vancouver General Hospital, Vancouver, BC, Canada.; Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Berchuck+A%22">Berchuck A</searchLink>; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Duke University Medical Center, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Brenton+JD%22">Brenton JD</searchLink>; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Campbell+I%22">Campbell I</searchLink>; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Cook+LS%22">Cook LS</searchLink>; Epidemiology, School of Public Health, University of Colorado, Aurora, CO, USA.; Community Health Sciences, University of Calgary, Calgary, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Doherty+JA%22">Doherty JA</searchLink>; Huntsman Cancer Institute, Department of Population Health Sciences, University of Utah, Salt Lake City, UT, USA.<br /><searchLink fieldCode="AU" term="%22Fasching+PA%22">Fasching PA</searchLink>; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Fortner+RT%22">Fortner RT</searchLink>; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Research, Cancer Registry of Norway, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Goodman+MT%22">Goodman MT</searchLink>; Cancer Prevention and Control Program, Cedars-Sinai Cancer, Cedars-Sinai Medical Center, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Gronwald+J%22">Gronwald J</searchLink>; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland.<br /><searchLink fieldCode="AU" term="%22Huntsman+DG%22">Huntsman DG</searchLink>; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.; British Columbia's Gynecological Cancer Research Team (OVCARE), University of British Columbia, BC Cancer, and Vancouver General Hospital, Vancouver, BC, Canada.; Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, BC, Canada.; Department of Molecular Oncology, BC Cancer Research Centre, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Karlan+BY%22">Karlan BY</searchLink>; David Geffen School of Medicine, Department of Obstetrics and Gynecology, University of California at Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kelemen+LE%22">Kelemen LE</searchLink>; Division of Acute Disease Epidemiology, South Carolina Department of Health & Environmental Control, Columbia, SC, USA.<br /><searchLink fieldCode="AU" term="%22Menon+U%22">Menon U</searchLink>; MRC Clinical Trials Unit, Institute of Clinical Trials and Methodology, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Modugno+F%22">Modugno F</searchLink>; Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Department of Epidemiology, University of Pittsburgh School of Public Health, Pittsburgh, PA, USA.; Women's Cancer Research Center, Magee-Womens Research Institute and Hillman Cancer Center, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Pharoah+PDP%22">Pharoah PDP</searchLink>; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.; Department of Computational Biomedicine, Cedars-Sinai Medical Center, West Hollywood, CA, USA.; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Schildkraut+JM%22">Schildkraut JM</searchLink>; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Sundfeldt+K%22">Sundfeldt K</searchLink>; Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Center for Cancer Research, University of Gothenburg, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Swerdlow+AJ%22">Swerdlow AJ</searchLink>; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.; Division of Breast Cancer Research, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Goode+EL%22">Goode EL</searchLink>; Department of Quantitative Health Sciences, Division of Epidemiology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22DeFazio+A%22">DeFazio A</searchLink>; The Daffodil Centre, The University of Sydney, a joint venture with Cancer Council NSW, Sydney, New South Wales, Australia.; Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney, New South Wales, Australia.; Department of Gynaecological Oncology, Westmead Hospital, Sydney, New South Wales, Australia.; The University of Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Köbel+M%22">Köbel M</searchLink>; Department of Pathology and Laboratory Medicine, University of Calgary, Foothills Medical Center, Calgary, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Ramus+SJ%22">Ramus SJ</searchLink>; School of Clinical Medicine, UNSW Medicine and Health, University of NSW Sydney, Sydney, New South Wales, Australia.; Adult Cancer Program, Lowy Cancer Research Centre, University of NSW Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Bowtell+DDL%22">Bowtell DDL</searchLink>; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Garsed+DW%22">Garsed DW</searchLink>; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.
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  Data: <searchLink fieldCode="JN" term="%22101767986%22">MedRxiv : the preprint server for health sciences</searchLink> [medRxiv] 2023 Nov 10. <i>Date of Electronic Publication: </i>2023 Nov 10.
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  Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101767986 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>NLM ISO Abbreviation: </i>medRxiv <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1101/2023.11.09.23298321
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        Text: English
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      – TitleFull: Concurrent RB1 loss and BRCA-deficiency predicts enhanced immunological response and long-term survival in tubo-ovarian high-grade serous carcinoma.
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              Text: 2023 Nov 10
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