Combined inhibition of MTAP and MAT2a mimics synthetic lethality in tumor models via PRMT5 inhibition.
Saved in:
| Title: | Combined inhibition of MTAP and MAT2a mimics synthetic lethality in tumor models via PRMT5 inhibition. |
|---|---|
| Authors: | Bedard GT; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, USA., Gilaj N; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, USA; Department of Chemistry, Lehman College, Bronx, New York, USA., Peregrina K; Department of Oncology, Albert Einstein College of Medicine, Bronx, New York, USA; Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, USA., Brew I; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, USA., Tosti E; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, USA; Department of Genetics, Albert Einstein College of Medicine, Bronx, New York, USA., Shaffer K; Ferrier Research Institute, Victoria University of Wellington, Lower Hutt, New Zealand., Tyler PC; Ferrier Research Institute, Victoria University of Wellington, Lower Hutt, New Zealand., Edelmann W; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, USA; Department of Genetics, Albert Einstein College of Medicine, Bronx, New York, USA., Augenlicht LH; Department of Oncology, Albert Einstein College of Medicine, Bronx, New York, USA; Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, USA., Schramm VL; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, USA. Electronic address: vern.schramm@einsteinmed.edu. |
| Source: | The Journal of biological chemistry [J Biol Chem] 2024 Jan; Vol. 300 (1), pp. 105492. Date of Electronic Publication: 2023 Nov 23. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
Be the first to leave a comment!
