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Ligand-based targeting of c-kit using engineered γδ T cells as a strategy for treating acute myeloid leukemia.

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Title: Ligand-based targeting of c-kit using engineered γδ T cells as a strategy for treating acute myeloid leukemia.
Authors: Branella GM; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.; Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, GA, United States.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States., Lee JY; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.; Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, GA, United States.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States., Okalova J; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States.; Molecular Systems Pharmacology Program, Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, GA, United States., Parwani KK; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.; Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, GA, United States.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States., Alexander JS; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States., Arthuzo RF; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.; Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, GA, United States.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States., Fedanov A; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States., Yu B; Expression Therapeutics, Inc., Tucker, GA, United States., McCarty D; Expression Therapeutics, Inc., Tucker, GA, United States., Brown HC; Expression Therapeutics, Inc., Tucker, GA, United States., Chandrakasan S; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States., Petrich BG; Expression Therapeutics, Inc., Tucker, GA, United States., Doering CB; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States.; Molecular Systems Pharmacology Program, Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, GA, United States., Spencer HT; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States.; Molecular Systems Pharmacology Program, Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, GA, United States.
Source: Frontiers in immunology [Front Immunol] 2023 Nov 13; Vol. 14, pp. 1294555. Date of Electronic Publication: 2023 Nov 13 (Print Publication: 2023).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1664-3224
DOI:10.3389/fimmu.2023.1294555