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Ligand-based targeting of c-kit using engineered γδ T cells as a strategy for treating acute myeloid leukemia.

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Title: Ligand-based targeting of c-kit using engineered γδ T cells as a strategy for treating acute myeloid leukemia.
Authors: Branella GM; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.; Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, GA, United States.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States., Lee JY; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.; Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, GA, United States.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States., Okalova J; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States.; Molecular Systems Pharmacology Program, Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, GA, United States., Parwani KK; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.; Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, GA, United States.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States., Alexander JS; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States., Arthuzo RF; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.; Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, GA, United States.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States., Fedanov A; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States., Yu B; Expression Therapeutics, Inc., Tucker, GA, United States., McCarty D; Expression Therapeutics, Inc., Tucker, GA, United States., Brown HC; Expression Therapeutics, Inc., Tucker, GA, United States., Chandrakasan S; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States., Petrich BG; Expression Therapeutics, Inc., Tucker, GA, United States., Doering CB; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States.; Molecular Systems Pharmacology Program, Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, GA, United States., Spencer HT; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States.; Molecular Systems Pharmacology Program, Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, GA, United States.
Source: Frontiers in immunology [Front Immunol] 2023 Nov 13; Vol. 14, pp. 1294555. Date of Electronic Publication: 2023 Nov 13 (Print Publication: 2023).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
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  Data: Ligand-based targeting of c-kit using engineered γδ T cells as a strategy for treating acute myeloid leukemia.
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  Data: <searchLink fieldCode="AU" term="%22Branella+GM%22">Branella GM</searchLink>; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.; Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, GA, United States.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States.<br /><searchLink fieldCode="AU" term="%22Lee+JY%22">Lee JY</searchLink>; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.; Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, GA, United States.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States.<br /><searchLink fieldCode="AU" term="%22Okalova+J%22">Okalova J</searchLink>; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States.; Molecular Systems Pharmacology Program, Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, GA, United States.<br /><searchLink fieldCode="AU" term="%22Parwani+KK%22">Parwani KK</searchLink>; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.; Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, GA, United States.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States.<br /><searchLink fieldCode="AU" term="%22Alexander+JS%22">Alexander JS</searchLink>; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States.<br /><searchLink fieldCode="AU" term="%22Arthuzo+RF%22">Arthuzo RF</searchLink>; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.; Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, GA, United States.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States.<br /><searchLink fieldCode="AU" term="%22Fedanov+A%22">Fedanov A</searchLink>; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States.<br /><searchLink fieldCode="AU" term="%22Yu+B%22">Yu B</searchLink>; Expression Therapeutics, Inc., Tucker, GA, United States.<br /><searchLink fieldCode="AU" term="%22McCarty+D%22">McCarty D</searchLink>; Expression Therapeutics, Inc., Tucker, GA, United States.<br /><searchLink fieldCode="AU" term="%22Brown+HC%22">Brown HC</searchLink>; Expression Therapeutics, Inc., Tucker, GA, United States.<br /><searchLink fieldCode="AU" term="%22Chandrakasan+S%22">Chandrakasan S</searchLink>; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States.<br /><searchLink fieldCode="AU" term="%22Petrich+BG%22">Petrich BG</searchLink>; Expression Therapeutics, Inc., Tucker, GA, United States.<br /><searchLink fieldCode="AU" term="%22Doering+CB%22">Doering CB</searchLink>; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States.; Molecular Systems Pharmacology Program, Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, GA, United States.<br /><searchLink fieldCode="AU" term="%22Spencer+HT%22">Spencer HT</searchLink>; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States.; Molecular Systems Pharmacology Program, Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, GA, United States.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2023 Nov 13; Vol. 14, pp. 1294555. <i>Date of Electronic Publication: </i>2023 Nov 13 (<i>Print Publication: </i>2023).
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        Value: 10.3389/fimmu.2023.1294555
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