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Engineered immunogens to elicit antibodies against conserved coronavirus epitopes.

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Title: Engineered immunogens to elicit antibodies against conserved coronavirus epitopes.
Authors: Kapingidza AB; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Marston DJ; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Harris C; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Wrapp D; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Winters K; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Mielke D; Department of Surgery, Duke University, Durham, NC, USA.; Center for Human Systems Immunology, Duke University, Durham, NC, USA., Xiaozhi L; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Yin Q; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Foulger A; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Parks R; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Barr M; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Newman A; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Schäfer A; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Eaton A; Department of Surgery, Duke University, Durham, NC, USA., Flores JM; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Harner A; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Catanzaro NJ Jr; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Mallory ML; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Mattocks MD; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Beverly C; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Rhodes B; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Mansouri K; Duke Human Vaccine Institute, Duke University, Durham, NC, USA., Van Itallie E; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Vure P; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Dunn B; Department of Surgery, Duke University, Durham, NC, USA., Keyes T; Department of Surgery, Duke University, Durham, NC, USA., Stanfield-Oakley S; Department of Surgery, Duke University, Durham, NC, USA., Woods CW; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA.; Center for Infectious Diseases and Diagnostic Innovation, Duke University Medical Center, Durham, NC, USA., Petzold EA; Center for Infectious Diseases and Diagnostic Innovation, Duke University Medical Center, Durham, NC, USA., Walter EB; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Pediatrics, Duke University, Durham, NC, USA., Wiehe K; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Edwards RJ; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Montefiori DC; Department of Surgery, Duke University, Durham, NC, USA., Ferrari G; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Surgery, Duke University, Durham, NC, USA.; Center for Human Systems Immunology, Duke University, Durham, NC, USA.; Department of Molecular Genetics and Microbiology, Duke University, Durham, NC, USA., Baric R; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Cain DW; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Saunders KO; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Surgery, Duke University, Durham, NC, USA.; Department of Molecular Genetics and Microbiology, Duke University, Durham, NC, USA.; Department of Immunology, Duke University, Durham, NC, USA., Haynes BF; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA.; Department of Immunology, Duke University, Durham, NC, USA., Azoitei ML; Duke Human Vaccine Institute, Duke University, Durham, NC, USA. mihai.azoitei@duke.edu.; Department of Medicine, Duke University, Durham, NC, USA. mihai.azoitei@duke.edu.
Source: Nature communications [Nat Commun] 2023 Nov 30; Vol. 14 (1), pp. 7897. Date of Electronic Publication: 2023 Nov 30.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-023-43638-9