Engineered immunogens to elicit antibodies against conserved coronavirus epitopes.
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| Title: | Engineered immunogens to elicit antibodies against conserved coronavirus epitopes. |
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| Authors: | Kapingidza AB; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Marston DJ; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Harris C; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Wrapp D; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Winters K; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Mielke D; Department of Surgery, Duke University, Durham, NC, USA.; Center for Human Systems Immunology, Duke University, Durham, NC, USA., Xiaozhi L; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Yin Q; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Foulger A; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Parks R; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Barr M; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Newman A; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Schäfer A; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Eaton A; Department of Surgery, Duke University, Durham, NC, USA., Flores JM; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Harner A; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Catanzaro NJ Jr; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Mallory ML; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Mattocks MD; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Beverly C; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Rhodes B; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Mansouri K; Duke Human Vaccine Institute, Duke University, Durham, NC, USA., Van Itallie E; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Vure P; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Dunn B; Department of Surgery, Duke University, Durham, NC, USA., Keyes T; Department of Surgery, Duke University, Durham, NC, USA., Stanfield-Oakley S; Department of Surgery, Duke University, Durham, NC, USA., Woods CW; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA.; Center for Infectious Diseases and Diagnostic Innovation, Duke University Medical Center, Durham, NC, USA., Petzold EA; Center for Infectious Diseases and Diagnostic Innovation, Duke University Medical Center, Durham, NC, USA., Walter EB; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Pediatrics, Duke University, Durham, NC, USA., Wiehe K; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Edwards RJ; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Montefiori DC; Department of Surgery, Duke University, Durham, NC, USA., Ferrari G; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Surgery, Duke University, Durham, NC, USA.; Center for Human Systems Immunology, Duke University, Durham, NC, USA.; Department of Molecular Genetics and Microbiology, Duke University, Durham, NC, USA., Baric R; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Cain DW; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA., Saunders KO; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Surgery, Duke University, Durham, NC, USA.; Department of Molecular Genetics and Microbiology, Duke University, Durham, NC, USA.; Department of Immunology, Duke University, Durham, NC, USA., Haynes BF; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA.; Department of Immunology, Duke University, Durham, NC, USA., Azoitei ML; Duke Human Vaccine Institute, Duke University, Durham, NC, USA. mihai.azoitei@duke.edu.; Department of Medicine, Duke University, Durham, NC, USA. mihai.azoitei@duke.edu. |
| Source: | Nature communications [Nat Commun] 2023 Nov 30; Vol. 14 (1), pp. 7897. Date of Electronic Publication: 2023 Nov 30. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 38036525 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Mielke+D%22">Mielke D</searchLink>; Department of Surgery, Duke University, Durham, NC, USA.; Center for Human Systems Immunology, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Xiaozhi+L%22">Xiaozhi L</searchLink>; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Yin+Q%22">Yin Q</searchLink>; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Foulger+A%22">Foulger A</searchLink>; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Parks+R%22">Parks R</searchLink>; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Barr+M%22">Barr M</searchLink>; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Newman+A%22">Newman A</searchLink>; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Schäfer+A%22">Schäfer A</searchLink>; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Eaton+A%22">Eaton A</searchLink>; Department of Surgery, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Flores+JM%22">Flores JM</searchLink>; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Harner+A%22">Harner A</searchLink>; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Catanzaro+NJ+Jr%22">Catanzaro NJ Jr</searchLink>; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Mallory+ML%22">Mallory ML</searchLink>; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Mattocks+MD%22">Mattocks MD</searchLink>; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Beverly+C%22">Beverly C</searchLink>; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Rhodes+B%22">Rhodes B</searchLink>; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Mansouri+K%22">Mansouri K</searchLink>; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Van+Itallie+E%22">Van Itallie E</searchLink>; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Vure+P%22">Vure P</searchLink>; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Dunn+B%22">Dunn B</searchLink>; Department of Surgery, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Keyes+T%22">Keyes T</searchLink>; Department of Surgery, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Stanfield-Oakley+S%22">Stanfield-Oakley S</searchLink>; Department of Surgery, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Woods+CW%22">Woods CW</searchLink>; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA.; Center for Infectious Diseases and Diagnostic Innovation, Duke University Medical Center, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Petzold+EA%22">Petzold EA</searchLink>; Center for Infectious Diseases and Diagnostic Innovation, Duke University Medical Center, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Walter+EB%22">Walter EB</searchLink>; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Pediatrics, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Wiehe+K%22">Wiehe K</searchLink>; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Edwards+RJ%22">Edwards RJ</searchLink>; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Montefiori+DC%22">Montefiori DC</searchLink>; Department of Surgery, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Ferrari+G%22">Ferrari G</searchLink>; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Surgery, Duke University, Durham, NC, USA.; Center for Human Systems Immunology, Duke University, Durham, NC, USA.; Department of Molecular Genetics and Microbiology, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Baric+R%22">Baric R</searchLink>; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Cain+DW%22">Cain DW</searchLink>; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Saunders+KO%22">Saunders KO</searchLink>; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Surgery, Duke University, Durham, NC, USA.; Department of Molecular Genetics and Microbiology, Duke University, Durham, NC, USA.; Department of Immunology, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Haynes+BF%22">Haynes BF</searchLink>; Duke Human Vaccine Institute, Duke University, Durham, NC, USA.; Department of Medicine, Duke University, Durham, NC, USA.; Department of Immunology, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Azoitei+ML%22">Azoitei ML</searchLink>; Duke Human Vaccine Institute, Duke University, Durham, NC, USA. mihai.azoitei@duke.edu.; Department of Medicine, Duke University, Durham, NC, USA. mihai.azoitei@duke.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2023 Nov 30; Vol. 14 (1), pp. 7897. <i>Date of Electronic Publication: </i>2023 Nov 30. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, N.I.H., Extramural – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. 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