SMARCB1 loss activates patient-specific distal oncogenic enhancers in malignant rhabdoid tumors.

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Title: SMARCB1 loss activates patient-specific distal oncogenic enhancers in malignant rhabdoid tumors.
Authors: Liu NQ; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Department of Hematology, Erasmus Medical Center (MC) Cancer Institute, Rotterdam, the Netherlands., Paassen I; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.; Oncode Institute, Utrecht, the Netherlands., Custers L; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.; Oncode Institute, Utrecht, the Netherlands., Zeller P; Oncode Institute, Utrecht, the Netherlands.; Hubrecht Institute-KNAW, Utrecht, the Netherlands.; University Medical Center Utrecht, Utrecht, the Netherlands., Teunissen H; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, the Netherlands., Ayyildiz D; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.; Oncode Institute, Utrecht, the Netherlands., He J; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.; Oncode Institute, Utrecht, the Netherlands., Buhl JL; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.; Oncode Institute, Utrecht, the Netherlands., Hoving EW; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands., van Oudenaarden A; Oncode Institute, Utrecht, the Netherlands.; Hubrecht Institute-KNAW, Utrecht, the Netherlands.; University Medical Center Utrecht, Utrecht, the Netherlands., de Wit E; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, the Netherlands. e.d.wit@nki.nl., Drost J; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands. J.Drost@prinsesmaximacentrum.nl.; Oncode Institute, Utrecht, the Netherlands. J.Drost@prinsesmaximacentrum.nl.
Source: Nature communications [Nat Commun] 2023 Dec 01; Vol. 14 (1), pp. 7762. Date of Electronic Publication: 2023 Dec 01.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-023-43498-3