Clostridioides difficile canonical L,D-transpeptidases catalyze a novel type of peptidoglycan cross-links and are not required for beta-lactam resistance.

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Title: Clostridioides difficile canonical L,D-transpeptidases catalyze a novel type of peptidoglycan cross-links and are not required for beta-lactam resistance.
Authors: Galley NF; School of Biosciences, University of Sheffield, Sheffield, UK., Greetham D; School of Biosciences, University of Sheffield, Sheffield, UK., Alamán-Zárate MG; School of Biosciences, University of Sheffield, Sheffield, UK., Williamson MP; School of Biosciences, University of Sheffield, Sheffield, UK., Evans CA; Department of Chemical and Biological Engineering, University of Sheffield, Sheffield, UK., Spittal WD; Department of Microbiology, Leeds Teaching Hospitals NHS Trust, Leeds Institute of Medical Research, University of Leeds, Leeds, UK; Healthcare Associated Infections Research Group, Leeds Institute of Medical Research University of Leeds, Leeds, UK., Buddle JE; School of Biosciences, University of Sheffield, Sheffield, UK., Freeman J; Department of Microbiology, Leeds Teaching Hospitals NHS Trust, Leeds Institute of Medical Research, University of Leeds, Leeds, UK; Healthcare Associated Infections Research Group, Leeds Institute of Medical Research University of Leeds, Leeds, UK., Davis GL; Department of Microbiology, Leeds Teaching Hospitals NHS Trust, Leeds Institute of Medical Research, University of Leeds, Leeds, UK; Healthcare Associated Infections Research Group, Leeds Institute of Medical Research University of Leeds, Leeds, UK., Dickman MJ; Department of Chemical and Biological Engineering, University of Sheffield, Sheffield, UK., Wilcox MH; Department of Microbiology, Leeds Teaching Hospitals NHS Trust, Leeds Institute of Medical Research, University of Leeds, Leeds, UK; Healthcare Associated Infections Research Group, Leeds Institute of Medical Research University of Leeds, Leeds, UK., Lovering AL; School of Biosciences, University of Birmingham, Birmingham, UK., Fagan RP; School of Biosciences, University of Sheffield, Sheffield, UK., Mesnage S; School of Biosciences, University of Sheffield, Sheffield, UK. Electronic address: s.mesnage@sheffield.ac.uk.
Source: The Journal of biological chemistry [J Biol Chem] 2024 Jan; Vol. 300 (1), pp. 105529. Date of Electronic Publication: 2023 Dec 01.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1083-351X
DOI:10.1016/j.jbc.2023.105529