A "suicide" BCG strain provides enhanced immunogenicity and robust protection against Mycobacterium tuberculosis in macaques.

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Title: A "suicide" BCG strain provides enhanced immunogenicity and robust protection against Mycobacterium tuberculosis in macaques.
Authors: Smith AA; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh PA.; The Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh PA., Su H; Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY 10021, USA.; Present address: Center for Veterinary Science, Zhejiang University, Hangzhou, China., Wallach J; Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY 10021, USA., Liu Y; Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY 10021, USA., Maiello P; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh PA.; The Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh PA., Borish HJ; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh PA.; The Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh PA., Winchell C; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh PA., Simonson AW; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh PA.; The Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh PA., Lin PL; The Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh PA.; Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, PA., Rodgers M; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh PA.; The Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh PA., Fillmore D; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh PA.; The Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh PA., Sakal J; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh PA.; The Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh PA., Lin K; Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY 10021, USA., Vinette V; Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY 10021, USA., Schnappinger D; Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY 10021, USA., Ehrt S; Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY 10021, USA., Flynn JL; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh PA.; The Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh PA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Sep 05. Date of Electronic Publication: 2024 Sep 05.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2692-8205
DOI:10.1101/2023.11.22.568105