Quantitative Systems Toxicology Modeling Informed Safe Dose Selection of Emvododstat in Acute Myeloid Leukemia Patients.
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| Title: | Quantitative Systems Toxicology Modeling Informed Safe Dose Selection of Emvododstat in Acute Myeloid Leukemia Patients. |
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| Authors: | Yang K; Quantitative Systems Pharmacology Solutions, Simulations Plus Inc., Research Triangle Park, North Carolina, USA., Kong R; PTC Therapeutics, Inc., South Plainfield, New Jersey, USA., Spiegel R; PTC Therapeutics, Inc., South Plainfield, New Jersey, USA., Baird JD; PTC Therapeutics, Inc., South Plainfield, New Jersey, USA., O'Keefe K; PTC Therapeutics, Inc., South Plainfield, New Jersey, USA., Howell BA; Quantitative Systems Pharmacology Solutions, Simulations Plus Inc., Research Triangle Park, North Carolina, USA., Watkins PB; UNC Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. |
| Source: | Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2024 Mar; Vol. 115 (3), pp. 525-534. Date of Electronic Publication: 2023 Dec 21. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1532-6535 |
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| DOI: | 10.1002/cpt.3136 |