Systems-based identification of the Hippo pathway for promoting fibrotic mesenchymal differentiation in systemic sclerosis.

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Title: Systems-based identification of the Hippo pathway for promoting fibrotic mesenchymal differentiation in systemic sclerosis.
Authors: Ma F; Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.; Division of Rheumatology, Dept of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., Tsou PS; Division of Rheumatology, Dept of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.; University of Michigan Scleroderma Program, Ann Arbor, MI, USA., Gharaee-Kermani M; Division of Rheumatology, Dept of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., Plazyo O; Division of Rheumatology, Dept of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., Xing X; Division of Rheumatology, Dept of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., Kirma J; Division of Rheumatology, Dept of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., Wasikowski R; Division of Rheumatology, Dept of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., Hile GA; Division of Rheumatology, Dept of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., Harms PW; Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Jiang Y; Department of Dermatology, University of Michigan, Ann Arbor, MI, USA., Xing E; Division of Rheumatology, Dept of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., Nakamura M; Department of Dermatology, University of Michigan, Ann Arbor, MI, USA., Ochocki D; Division of Rheumatology, Dept of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.; University of Michigan Scleroderma Program, Ann Arbor, MI, USA., Brodie WD; Division of Rheumatology, Dept of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., Pillai S; Ragon Institute, Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Boston, MA, USA., Maverakis E; Department of Dermatology, University of California, Davis, Sacramento, CA, USA., Pellegrini M; Dept of Molecular, Cell, and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA., Modlin RL; Dept of Molecular, Cell, and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA.; Division of Dermatology, Department of Medicine, University of California, Los Angeles, CA, 90095, USA., Varga J; Division of Rheumatology, Dept of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.; University of Michigan Scleroderma Program, Ann Arbor, MI, USA., Tsoi LC; Department of Dermatology, University of Michigan, Ann Arbor, MI, USA., Lafyatis R; Division of Rheumatology, University of Pittsburgh, Pittsburgh, PA, USA., Kahlenberg JM; Division of Rheumatology, Dept of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., Billi AC; Department of Dermatology, University of Michigan, Ann Arbor, MI, USA., Khanna D; Division of Rheumatology, Dept of Internal Medicine, University of Michigan, Ann Arbor, MI, USA. khannad@med.umich.edu.; University of Michigan Scleroderma Program, Ann Arbor, MI, USA. khannad@med.umich.edu., Gudjonsson JE; Department of Dermatology, University of Michigan, Ann Arbor, MI, USA. johanng@med.umich.edu.
Source: Nature communications [Nat Commun] 2024 Jan 03; Vol. 15 (1), pp. 210. Date of Electronic Publication: 2024 Jan 03.
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-023-44645-6