The BCKDH kinase inhibitor BT2 promotes BCAA disposal and mitochondrial proton leak in both insulin-sensitive and insulin-resistant C2C12 myotubes.

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Title: The BCKDH kinase inhibitor BT2 promotes BCAA disposal and mitochondrial proton leak in both insulin-sensitive and insulin-resistant C2C12 myotubes.
Authors: Rivera CN; Department of Health and Human Performance, High Point University, High Point, North Carolina, USA., Smith CE; Department of Health and Human Performance, High Point University, High Point, North Carolina, USA., Draper LV; Department of Health and Human Performance, High Point University, High Point, North Carolina, USA., Kee ME; Department of Health and Human Performance, High Point University, High Point, North Carolina, USA., Cook NE; Department of Health and Human Performance, High Point University, High Point, North Carolina, USA., McGovern MR; Department of Health and Human Performance, High Point University, High Point, North Carolina, USA., Watne RM; Department of Chemistry, High Point University, High Point, North Carolina, USA., Wommack AJ; Department of Chemistry, High Point University, High Point, North Carolina, USA., Vaughan RA; Department of Health and Human Performance, High Point University, High Point, North Carolina, USA.
Source: Journal of cellular biochemistry [J Cell Biochem] 2024 Mar; Vol. 125 (3), pp. e30520. Date of Electronic Publication: 2024 Jan 16.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8205768 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4644 (Electronic) Linking ISSN: 07302312 NLM ISO Abbreviation: J Cell Biochem Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1097-4644
DOI:10.1002/jcb.30520