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Acetyl-CoA production by Mediator-bound 2-ketoacid dehydrogenases boosts de novo histone acetylation and is regulated by nitric oxide.

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Title: Acetyl-CoA production by Mediator-bound 2-ketoacid dehydrogenases boosts de novo histone acetylation and is regulated by nitric oxide.
Authors: Russo M; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy. Electronic address: marta.russo@ieo.it., Gualdrini F; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy. Electronic address: francesco.gualdrini@ieo.it., Vallelonga V; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy., Prosperini E; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy., Noberini R; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy., Pedretti S; DiSFeB, Dipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, Milano 20133, Italy., Borriero C; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy., Di Chiaro P; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy., Polletti S; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy., Imperato G; DiSFeB, Dipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, Milano 20133, Italy., Marenda M; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy., Ghirardi C; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy., Bedin F; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy., Cuomo A; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy., Rodighiero S; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy., Bonaldi T; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy; Department of Hematology and Hematology-Oncology (DIPO), Università degli Studi di Milano, Milano 20122, Italy., Mitro N; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy; DiSFeB, Dipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, Milano 20133, Italy., Ghisletti S; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy. Electronic address: serenamarialuisa.ghisletti@ieo.it., Natoli G; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy. Electronic address: gioacchino.natoli@ieo.it.
Source: Molecular cell [Mol Cell] 2024 Mar 07; Vol. 84 (5), pp. 967-980.e10. Date of Electronic Publication: 2024 Jan 18.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Acetyl-CoA production by Mediator-bound 2-ketoacid dehydrogenases boosts de novo histone acetylation and is regulated by nitric oxide.
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  Data: <searchLink fieldCode="AU" term="%22Russo+M%22">Russo M</searchLink>; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy. Electronic address: marta.russo@ieo.it.<br /><searchLink fieldCode="AU" term="%22Gualdrini+F%22">Gualdrini F</searchLink>; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy. Electronic address: francesco.gualdrini@ieo.it.<br /><searchLink fieldCode="AU" term="%22Vallelonga+V%22">Vallelonga V</searchLink>; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy.<br /><searchLink fieldCode="AU" term="%22Prosperini+E%22">Prosperini E</searchLink>; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy.<br /><searchLink fieldCode="AU" term="%22Noberini+R%22">Noberini R</searchLink>; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy.<br /><searchLink fieldCode="AU" term="%22Pedretti+S%22">Pedretti S</searchLink>; DiSFeB, Dipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, Milano 20133, Italy.<br /><searchLink fieldCode="AU" term="%22Borriero+C%22">Borriero C</searchLink>; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Chiaro+P%22">Di Chiaro P</searchLink>; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy.<br /><searchLink fieldCode="AU" term="%22Polletti+S%22">Polletti S</searchLink>; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy.<br /><searchLink fieldCode="AU" term="%22Imperato+G%22">Imperato G</searchLink>; DiSFeB, Dipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, Milano 20133, Italy.<br /><searchLink fieldCode="AU" term="%22Marenda+M%22">Marenda M</searchLink>; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy.<br /><searchLink fieldCode="AU" term="%22Ghirardi+C%22">Ghirardi C</searchLink>; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy.<br /><searchLink fieldCode="AU" term="%22Bedin+F%22">Bedin F</searchLink>; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy.<br /><searchLink fieldCode="AU" term="%22Cuomo+A%22">Cuomo A</searchLink>; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy.<br /><searchLink fieldCode="AU" term="%22Rodighiero+S%22">Rodighiero S</searchLink>; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy.<br /><searchLink fieldCode="AU" term="%22Bonaldi+T%22">Bonaldi T</searchLink>; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy; Department of Hematology and Hematology-Oncology (DIPO), Università degli Studi di Milano, Milano 20122, Italy.<br /><searchLink fieldCode="AU" term="%22Mitro+N%22">Mitro N</searchLink>; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy; DiSFeB, Dipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, Milano 20133, Italy.<br /><searchLink fieldCode="AU" term="%22Ghisletti+S%22">Ghisletti S</searchLink>; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy. Electronic address: serenamarialuisa.ghisletti@ieo.it.<br /><searchLink fieldCode="AU" term="%22Natoli+G%22">Natoli G</searchLink>; Department of Experimental Oncology, European Institute of Oncology (IEO) IRCCS, Milan 20139, Italy. Electronic address: gioacchino.natoli@ieo.it.
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  Data: <searchLink fieldCode="JN" term="%229802571%22">Molecular cell</searchLink> [Mol Cell] 2024 Mar 07; Vol. 84 (5), pp. 967-980.e10. <i>Date of Electronic Publication: </i>2024 Jan 18.
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        Value: 10.1016/j.molcel.2023.12.033
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              Text: 2024 Mar 07
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