Nivolumab receptor occupancy on effector regulatory T cells predicts clinical benefit.
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| Title: | Nivolumab receptor occupancy on effector regulatory T cells predicts clinical benefit. |
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| Authors: | Hosonuma M; Department of Clinical Immuno Oncology, Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa University, Setagaya-Ku, Japan.; Division of Medical Pharmacology, Department of Pharmacology, School of Medicine, Showa University, Setagaya-Ku, Japan.; Pharmacological Research Center, Showa University, Setagaya-Ku, Japan.; Division of Medical Oncology, Department of Medicine, School of Medicine, Showa University, Setagaya-Ku, Japan., Hirasawa Y; Division of Medical Oncology, Department of Medicine, School of Medicine, Showa University, Setagaya-Ku, Japan., Kuramasu A; Department of Clinical Immuno Oncology, Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa University, Setagaya-Ku, Japan., Murayama M; Department of Clinical Immuno Oncology, Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa University, Setagaya-Ku, Japan.; Division of Medical Pharmacology, Department of Pharmacology, School of Medicine, Showa University, Setagaya-Ku, Japan.; Pharmacological Research Center, Showa University, Setagaya-Ku, Japan.; Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Showa University, Setagaya-Ku, Japan.; Head and Neck Oncology Center, Showa University, Setagaya-Ku, Japan., Narikawa Y; Department of Clinical Immuno Oncology, Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa University, Setagaya-Ku, Japan.; Division of Medical Pharmacology, Department of Pharmacology, School of Medicine, Showa University, Setagaya-Ku, Japan.; Pharmacological Research Center, Showa University, Setagaya-Ku, Japan.; Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Showa University, Setagaya-Ku, Japan.; Head and Neck Oncology Center, Showa University, Setagaya-Ku, Japan.; Department of Otorhinolaryngology, Fujigaoka Hospital, Yokohama, Japan., Toyoda H; Department of Clinical Immuno Oncology, Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa University, Setagaya-Ku, Japan.; Division of Medical Pharmacology, Department of Pharmacology, School of Medicine, Showa University, Setagaya-Ku, Japan.; Pharmacological Research Center, Showa University, Setagaya-Ku, Japan.; Department of Otorhinolaryngology, Fujigaoka Hospital, Yokohama, Japan.; Department of Orthopedic Surgery, School of Medicine, Showa University, Setagaya-Ku, Japan., Baba Y; Department of Clinical Immuno Oncology, Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa University, Setagaya-Ku, Japan., Isobe J; Department of Hospital Pharmaceutics, School of Pharmacy, Showa University, Setagaya-Ku, Japan., Funayama E; Department of Clinical Immuno Oncology, Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa University, Setagaya-Ku, Japan., Tajima K; Department of Clinical Immuno Oncology, Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa University, Setagaya-Ku, Japan., Shida M; Department of Clinical Immuno Oncology, Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa University, Setagaya-Ku, Japan., Hamada K; Division of Medical Oncology, Department of Medicine, School of Medicine, Showa University, Setagaya-Ku, Japan., Tsurui T; Division of Medical Oncology, Department of Medicine, School of Medicine, Showa University, Setagaya-Ku, Japan., Ariizumi H; Division of Medical Oncology, Department of Medicine, School of Medicine, Showa University, Setagaya-Ku, Japan., Ishiguro T; Division of Medical Oncology, Department of Medicine, School of Medicine, Showa University, Setagaya-Ku, Japan., Suzuki R; Division of Medical Oncology, Department of Medicine, School of Medicine, Showa University, Setagaya-Ku, Japan., Ohkuma R; Division of Medical Oncology, Department of Medicine, School of Medicine, Showa University, Setagaya-Ku, Japan., Kubota Y; Division of Medical Oncology, Department of Medicine, School of Medicine, Showa University, Setagaya-Ku, Japan., Horiike A; Division of Medical Oncology, Department of Medicine, School of Medicine, Showa University, Setagaya-Ku, Japan., Sambe T; Division of Clinical Pharmacology, Department of Pharmacology, School of Medicine, Showa University, Setagaya-Ku, Japan., Tsuji M; Pharmacological Research Center, Showa University, Setagaya-Ku, Japan., Wada S; Department of Clinical Diagnostic Oncology, Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa University, Setagaya-Ku, Japan., Kiuchi Y; Division of Medical Pharmacology, Department of Pharmacology, School of Medicine, Showa University, Setagaya-Ku, Japan.; Pharmacological Research Center, Showa University, Setagaya-Ku, Japan., Kobayashi S; Head and Neck Oncology Center, Showa University, Setagaya-Ku, Japan.; Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa University, Setagaya-Ku, Japan., Tsunoda T; Division of Medical Oncology, Department of Medicine, School of Medicine, Showa University, Setagaya-Ku, Japan., Yoshimura K; Department of Clinical Immuno Oncology, Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa University, Setagaya-Ku, Japan.; Division of Medical Oncology, Department of Medicine, School of Medicine, Showa University, Setagaya-Ku, Japan. |
| Source: | Cancer science [Cancer Sci] 2024 Mar; Vol. 115 (3), pp. 752-762. Date of Electronic Publication: 2024 Jan 22. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley Publishing on behalf of the Japanese Cancer Association Country of Publication: England NLM ID: 101168776 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1349-7006 (Electronic) Linking ISSN: 13479032 NLM ISO Abbreviation: Cancer Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1349-7006 |
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| DOI: | 10.1111/cas.16061 |
