The critical role of neutrophil-endothelial cell interactions in sepsis: new synergistic approaches employing organ-on-chip, omics, immune cell phenotyping and in silico modeling to identify new therapeutics.

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Title: The critical role of neutrophil-endothelial cell interactions in sepsis: new synergistic approaches employing organ-on-chip, omics, immune cell phenotyping and in silico modeling to identify new therapeutics.
Authors: Liu D; Department of Bioengineering, Temple University, Philadelphia, PA, United States., Langston JC; Department of Bioengineering, Temple University, Philadelphia, PA, United States., Prabhakarpandian B; Biomedical and Data Sciences Division, CFD Research Corporation, Huntsville, AL, United States., Kiani MF; Department of Bioengineering, Temple University, Philadelphia, PA, United States.; Department of Mechanical Engineering, Temple University, Philadelphia, PA, United States.; Department of Radiation Oncology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, United States., Kilpatrick LE; Center for Inflammation and Lung Research, Department of Microbiology, Immunology and Inflammation, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, United States.
Source: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2024 Jan 08; Vol. 13, pp. 1274842. Date of Electronic Publication: 2024 Jan 08 (Print Publication: 2023).
Publication Type: Journal Article; Review; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
Journal Info: Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 101585359 Publication Model: eCollection Cited Medium: Internet ISSN: 2235-2988 (Electronic) Linking ISSN: 22352988 NLM ISO Abbreviation: Front Cell Infect Microbiol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2235-2988
DOI:10.3389/fcimb.2023.1274842